An important question in auditory neuroscience concerns how the neural representation of sound features changes from the periphery to the cortex. Here we focused on the encoding of sound onsets and we used a modeling approach to explore the degree to which auditory cortical neurons follow a similar envelope integration mechanism found at the auditory periphery. Our "forward" model was able to p...

Subset currents on hyperbolic groups were introduced by Kapovich and Nagnibeda as a generalization of geodesic groups, which Bonahon have been successfully studied in the case fundamental group <mml:...

Arteriolar tortuousities, consisting of vascular coils, loops, and spirals, appear in white matter in a subset of human cerebral vessels. Computerized morphometry was used to analyze brain sections from a broad age range of subjects to determine whether tortuosity is a phenomenon of aging or is associated with leukoaraiosis (LA) or Alzheimer disease (AD). Autopsy brains were studied from 55 sub...

Patients with symptoms caused by hypertrophic obstructive cardiomyopathy are treated with β-blockers, verapamil, and disopyramide. Novel drugs are under development. The minority of patients whose symptoms interfere substantially with lifestyle despite optimal pharmacological management may be offered septal reduction therapy with ablation or myectomy. Other mechanical therapies, including shor...