background: p2x4 receptor (p2x4r), a purinoceptor expressed in activated spinal microglia, plays a key role in the pathogenesis of neuropathic pain. spinal nerve injury induces up-regulation of p2x4r on activated microglia in the spinal cord, and blockade of this receptor can reduce neuropathic pain. the present study was undertaken to determine whether paroxetine, an inhibitor of p2x4r, could ...

Sepiolite deposits have been recently discovered in northeastern Iran. However, there is still little information about its physicochemical and mineralogical characteristics. Therefore, the collapse of the sepiolite (with sizes of < 63 μm) structure induced by temperature elevation in an electric furnace at 350, 550, and 850 °C for 4 hours was studied using X-ray diffraction (XRD) in combinatio...

It is a common misperception that—because space is cold—an object initially at room temperature will cool in space. However, this is true only at night (that is, when the object is in the Earth’s shadow). Only then will the equilibrium temperature of any object in space be well below room temperature. During the daytime, the equilibrium temperature can be either above or below room temperature....