BACKGROUND Use of self-administered vaginal swabs (SAS) for the detection of Chlamydia trachomatis by nucleic acid amplification tests simplifies specimen collection and transport, especially for women in nonclinical settings. GOAL We investigated the preference and comfort level of military women for the collection of SAS, compared with urine, for the diagnosis of genital chlamydial infectio...

Substrates of aldehyde oxidase (AO), for which human clinical pharmacokinetics are reported, were selected and evaluated in pooled mixed-gender cryopreserved human hepatocytes in an effort to quantitatively characterize AO activity. Estimated hepatic clearance (Cl(h)) for BIBX1382, carbazeran, O⁶-benzylguanine, zaleplon, and XK-469 using cryopreserved hepatocytes was 18, 17, 12, <4.3, and <4.3 ...

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There is a considerable interest in low activation and high heat resistant materials for fusion applications. Tungsten (W) would fulfill these requirements for plasma facing components of future fusion power plants. A novel method developed by SNL to enhance the thermal and dimensional stability of W requires depositing materials such as Re and Mo as a thin coating on the surface of dendritic W...