Technetium-99m (Tc-99m) teboroxime is a new perfusion tracer that is highly extracted and rapidly cleared by the myocardium. To determine the feasibility of Tc-99m teboroxime imaging in the diagnosis of patients with suspected coronary artery disease, 30 patients underwent single photon emission computed tomography imaging with Tc-99m teboroxime (25.2 +/- 1 mCi) at peak exercise and again 60 mi...

An electrochemical hydride generation (ECHG) technique was developed to improve the determination of thallium by atomic spectrometry. The technique is based on the catholyte variation system for production of thallium hydride. Using Pb-Sn alloy as cathode, a transient peak shaped signal was achieved and its height, the maximum absorbance value, was taken as an analytical parameter. Parameters t...

Slow Inward Current, Thallium Intoxication, Voltage Clamp, Available Intracellular Energy To conclude our investigation of thallium effects on cardiac tissues, we studied the slow inward current of sheep cardiac Purkinje fibres exposed to 10“7 to 105 m Tl+ for extended periods of up to 80 min. Our previous results had suggested a possible involvement of the slow inward current during thallium i...

Fifty-two patients with suspected coronary artery disease underwent coronary angiography, thallium-201 myocardial imaging, and ECG-gated blood pool ventriculography at rest and at maximal exercise. In 11 patients without coronary artery disease, all thallium images were normal. The resting ejection fraction (EF) was normal in all 11 patients and increased during exercise in six, was unchanged i...

This study assesses the relationship between the distribution of thallium-201 and myocardial blood flow during coronary vasodilation induced by intravenous dipyridamole in canine models of partial and complete coronary artery stenosis. 10 dogs were chronically instrumented with catheters in the left atrium and aorta and with a balloon occluder and electromagnetic flow probe on the proximal left...

Fifty-two patients with suspected coronary artery disease underwent coronary angiography, thallium-201 myocardial imaging, and ECG-gated blood pool ventriculography at rest and at maximal exercise. In 11 patients without coronary artery disease, all thallium images were normal. The resting ejection fraction (EF) was normal in all 11 patients and increased during exercise in six, was unchanged i...

The following case report of thallium poisoning is of interest from several points of view. It emphasizes the effect of thallium on the renal and vascular systems and its role as a possible cause of hypertension even in childhood; it indicates that a complete cure may be obtained without the use of dimercaprol (B.A.L.); and it affords scope for discussion of the possible mechanisms whereby, in ...

Thallium tomographic imaging and exercise electrocardiography were performed on 136 diabetic patients without symptoms of heart disease. Thirty three patients had post-exercise thallium defects and 19 had ST 1 mm greater than or equal to segment depression during exercise electrocardiography. Both tests were positive in 13 patients. Coronary angiography was subsequently performed on 33 patients...