نتایج جستجو برای: tgf β1smad2

تعداد نتایج: 27409  

Journal: :hepatitis monthly 0
hossein khorramdelazad molecular medicine research center, rafsanjan university of medical sciences, rafsanjan, ir iran gholamhossein hassanshahi molecular medicine research center, rafsanjan university of medical sciences, rafsanjan, ir iran behzad nasiri ahmadabadi immunology of infectious diseases research center, rafsanjan university of medical sciences, rafsanjan, ir iran mohammad kazemi arababadi immunology of infectious diseases research center, rafsanjan university of medical sciences, rafsanjan, ir iran; corresponding author: mohammad kazemi arababadi, immunology of infectious diseases research center, rafsanjan university of medical sciences, rafsanjan, ir iran. tel.: +98-3915234003-5, fax: +98-3915225209, e-mail:

results our results revealed that the serum levels of tgf-β were significantly increased in chb patients in compare to healthy controls. conclusions according to this result, it may be concluded that high serum levels of tgf-β may be a mechanism by which immune response against hbv is suppressed. background the transforming growth factor-β (tgf-β) is an important cytokine with anti-inflammatory...

Journal: :African Journal of Urology 2021

Abstract Background To compare the urinary biomarkers—beta 2-microglobulin (β2M), monocyte chemotactic peptide-1 (MCP-1), and transforming growth factor-beta (TGF-β1)—in outcome assessment of children with pelviureteric junction obstruction (PUJO) undergoing pyeloplasty. Methods A prospective study was conducted on PUJO who had pyeloplasty in a tertiary care center from July 2016 to March 2018....

Ali Ramazani, Alireza Biglari, Javad Tavkoli Bazzaz Maryam Foroutan Jazi Mehdi Eskandari Paul Kingston Saeideh Mazloomzadeh

Objective(s):Diabetic nephropathy is an important long-term complication of diabetes mellitus which appears to be partially mediated by an increase in secretion of transforming growth factor-β (TGF-β). Fibromodulin, the small leucine-rich proteoglycan, has been proposed to be the potent TGFβ1 modulator. In this study, the therapeutic effects of recombinant adenoviral vectors expressing fibromod...

ستاری, ماندانا, طبیب‌زاده نوری, زهره, عرفانیان, بهناز,

سابقه و هدف: TGF-β1 یکی از فاکتورهای رشد است که در کنترل عملکرد سلولی در هر دو حالت سلامت و بیماری نقش دارد. ‏اما چگونگی اثر سیگار بر سطح و غلظت این سایتوکاین در مایع شیار لثه‌ای‏‏، همچنان ناشناخته باقی مانده است. هدف از این مطالعه بررسی رابطه مصرف سیگار با غلظت TGF-β1 موجود در مایع شیار لثه‌ای در بیماران مبتلا به پریودنتیت مزمن متوسط تا شدید بود. مواد و روشها: در مطالعه تحلیلی و مورد-شاهدی حاض...

Background: TNF-α is a multifunctional proinflammatory cytokine and TGF-β1 is a secretory protein controlling epithelial proliferation and differentiation. Keratocyst presents an aggressive behavior and a growth mechanism different from that of radicular cyst. Aim: In this line, the present study aimed at evaluating TNF-α and TGF-β1 level and its association with histopath...

Journal: :Food Science and Technology 2022

Transforming growth factor β1 (TGF-β1) is a polypeptide with various biological activities. Recent studies have shown that this and they receptors are expressed in human Leydig cells, Sertoli spermatogonia, spermatocytes sperm cells after birth, involved the endocrine regulation of spermatogenesis. However, there no report on expression TGF-β embryonic testis. TGF-β1 peptide widely distributed ...

Journal: :iranian journal of pathology 2006
m.hossein ghaini t ghazanfari n fallah

objective: helicobacter pylori has a well-established role in the development of gastric cancer. in vitro studies reveal increased proliferation of the gastric mucosa in the presence of h. pylori infection. it has been also shown that production of some cytokines, such as interleukin-1 beta (il-1b) is increased in h. pylori infection. in addition, il-1b increases proliferation of gastric epithe...

Background: Ageing and physical inactivity can negatively affect immune system. On the contrary, a healthy lifestyle and physical activity can improve immune system and prevent from mild inflammatory diseases. Transforming Growth Factor-β (TGF-β) can play an important role in the regulation of immune function and inflammation. This study aimed to investigate the effects of 8 weeks of theraband ...

Journal: :IOP conference series 2023

Abstract The carbon-to-nitrogen ratio of organic matter refers to the proportion carbon nitrogen present and is basis for determining quality ameliorant. Amelioration technology a solution increasing soil plant productivity in an agricultural area using local resources (biomass waste). This study aims determine estimated C/N formulation research used completely randomised design with three repl...

ژورنال: :پوست و زیبایی 0
عیسی خواهشی isa khaheshi tehran university of medical science, tehran, iran. center for research in chemical injuries, baqiyaمرکز تحقیقات آسیب های شیمیایی، دانشگاه علوم پزشکی بقیه ا... (عج)، تهران، ایران سعید کشاورز saeeid keshavarz center for research in chemical injuries, baqiyatallah university of medical sciences, tehran, iranمرکز تحقیقات آسیب های شیمیایی، دانشگاه علوم پزشکی بقیه ا... (عج)، تهران، ایران مجید شهرتی majid shohrati center for research in chemical injuries, baqiyatallah university of medical sciences, tehran, iranمرکز تحقیقات آسیب های شیمیایی، دانشگاه علوم پزشکی بقیه ا... (عج)، تهران، ایران عباسعلی فولادی ایمانی abbasali fooladi imani center for research in chemical injuries, baqiyatallah university of medical sciences, tehran, iranمرکز تحقیقات آسیب های شیمیایی، دانشگاه علوم پزشکی بقیه ا... (عج)، تهران، ایران محمدرضا نورانی mohammadreza nourani center for research in chemical injuries, baqiyatallah university of medical sciences, tehran, iranمرکز تحقیقات آسیب های شیمیایی، دانشگاه علوم پزشکی بقیه ا... (عج)، تهران، ایران

زمینه و هدف: گاز خردل به عنوان گاز تاول زا موجب آسیب های متنوعی در اعضای مختلف بدن از جمله پوست می شود که موجب تغییر در اجزای سلولی از جمله dna و تظاهرات بالینی شایع از جمله خارش مزمن می گردد. ملکول tgf-β1 به عنوان یک سیتوکین با اعمال متنوع از جمله مهار رشد سلولی و تعدیل و سرکوب التهاب نقش مهمی در پروسه التهاب پوستی ایفا می کند به طوری که نقش ضد التهابی این ملکول و گیرنده های آن در التهاب پوستی...

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