In exploring the role of the chloroplast in the multiplication of turnip yellow mosaic virus, the biosyntheses of the major viral polyamine, spermidine, as well as that of the tetramine, spermine were studied. The synthesis of these polyamines from [2-(14)C]methionine in protoplasts of Chinese cabbage leaf cells derived from healthy plants or those infected by turnip yellow mosaic virus were ex...

Objective(s): Recently, bone-avid radiopharmaceuticals have been shown to have potential benefits for the treatment of widespread bone metastases. Although 177Lutriethylene tetramine hexa methylene phosphonic acid (abbreviated as 177Lu- TTHMP), as an agent for bone pain palliation, has been evaluated in previous studies, there are large discrepancies between the obtained results. In this study,...

Tb evaluate tests for behaviora] teratology in animals, brain dysfunction caused by maternal environmental ugents is compared both epidemio]egical]y and experimental[y. Ethanol: The features of CNS involvement in human FAS (fetul alcohol syndrome) and FAE (fetal alcoho] effects) are developmental delay and intellectual impairment. One of thc most vulnerablc structures in the rat fetus exposed t...

Polyamine oxidase from Avena sativa L. cv. Cristal seedlings was purified to homogeneity using a simple four-step purification protocol including an infiltration washing technique. The enzyme had a high affinity for spermidine and spermine (K(m) approximately 5.5 and 1.2 microM, respectively), and also oxidized norspermidine (K(m) approximately 64.0 microM). Natural and synthetic diamines, cycl...

The most commonly occurring of the natural polyamines are putrescine [ Nl ll(CI ll),N14?, a diaminel, spermidine [ Nl 12(C€12)3Nl l(C142),NIIl. a triamine] and spermine [ Nl il(Cl 12);NI l(C€Il),N€I(CI 1?)?NI ?. a tetramine]. One or more of these compounds are present in every living cell. All are found in eukaryotes; spermine is absent from most prokaryotes. The polyamines are essential for ce...

P UTRESCINE has been found to induce chromosome aberrations in cells undergoing meiosis in Oenothera [8] but not in cells undergoing mitosis in roots of Vicia faba [9]. In re-examining the action of putrescine and cadaverine in less toxic concentrations [cf. 91, we have tested the ability of these polyamines either to induce chromosome breakage or to upset the process of chromosome condensation...

objective(s): recently, bone-avid radiopharmaceuticals have been shown to have potential benefits for the treatment of widespread bone metastases. although 177lutriethylene tetramine hexa methylene phosphonic acid (abbreviated as 177lu- tthmp), as an agent for bone pain palliation, has been evaluated in previous studies, there are large discrepancies between the obtained results. in this study,...