Drug resistance in Plasmodium falciparum parasites is associated with the single nucleotide polymorphism (SNP) exo-E415G, which considered as a marker to reduce susceptibility artimisinin and leads treatment failure. This study aims establish procedure based on tetra-primer ARMS PCR technique detect SNP exo-E415G malaria patients who experienced failure artemisinin. DNA sample from P. 3D7 isola...

Sugarcane is a major crop for sugar production around the world. The complexity of sugarcane genome creates challenges use both conventional and molecular breeding methods to improve at genetic level. DNA sequencing an important tool assess how genus Saccharum genera complex are interrelated. Here, we identify kinship Nepal2013-6 (Saccharum spontaneum, x = 10) using tetra-primer amplification r...

The reaction of tetra-kis-(all-yloxy)calix[4]arene with the first-generation Grubbs catalyst, followed by catalytic hydrogenation, gave the novel bis-calixarene 15,20,46,51,64,69,74,79-octa-oxatridecacyclo[32.28.8.8(3,28).1(13,53).1(22,44).0(9,14).0(21,26).0(38,70).0(40,45).0(52,57).0(59,63).0(7,80).0(32,73)]octa-conta-1(63),3,5,7(80),9(14),10,12,21,23,25,28(73),29,31,34,36,38(70),40,42,44,52,5...

PURPOSE Asthma is the most prevalent disease in India according to the national survey conducted by NFHS 2 in 1998-1999. Matrix metalloproteinase-2 (MMP-2), a collagenase encoded by the MMP-2 gene, degrades the type IV collagen and is responsible for inflammatory responses. This is a pilot study evaluating the role of MMP-2 -1306C/T promoter single nucleotide polymorphism (SNP) in asthma pathog...

BACKGROUND Asthma is the most prevalent disease in India according to the national survey conducted by NFHS 2 in 1998-399. Prostaglandin D2 (PGD2) is a bronchoconstriction inducing metabolite of arachidonic acid in the mast cells, which is produced on exposure to allergens and acts as a ligand for the Prostaglandin D2 Receptor (PTGDR). Polymorphisms in the PTGDR gene have been suggested to be i...