Colistin is one of the last-resort therapeutic antibiotics used to control carbapenem-resistant Klebsiella pneumoniae. However, emergence colistin-resistant strains with high mortality and morbidity has become a new challenge. Therefore, it crucial characterize genotypic features carbapenem- K. pneumoniae (CCKP) isolates implement public health intervention strategies. In this study, we analyze...

Background: Shiga toxin-producing Escherichia coli (STEC) strains are considered to be most common food-borne enteric zoonotic pathogen, causing various disease conditions in both animals and humans highly pathogenic human low infectious doses. Resistance against antibiotics by STEC is also a big concern now days. Hence view of the public health significance STEC, present work was planned know ...

Vibrio vulnificus, parahaemolyticus and harveyi are the causative agents of most severe diseases marine brackish aquaculture systems. These also associated with serious ailments in humans. The present paper unravels virulence features/genes antimicrobial resistance (AMR) phenotypes/genes these spp. isolated from natural disease outbreaks marine/estuarine fishes India for first time. Results on ...

Background: Many bacteria can cause urinary tract infections (UTIs), among which Escherichia coli is the most common causative agent. strains are divided into eight phylogenetic groups based on new Quadroplex-PCR method, different in terms of patterns resistance to antibiotics, virulence, and environmental characteristics. Objectives: This study aimed determine prevalence drug genes E. causing ...

The development of antimicrobial resistance in foodborne pathogens is a growing public health concern. This study was undertaken to determine the susceptibility Salmonella enterica subspecies isolated from Australian commercial egg layer industry. S. (n=307) flock environments (2015–2018) were obtained reference, research and State Government laboratories six states. All isolates serotyped. Ant...

Abstract Background The discovery of the superbug mcr-1 -positive Escherichia coli (MCRPEC) has drew greet attention. Swine-origin multi-drug resistant MCRPEC been a potential threat to public health and safety. However, there were few detailed studies have reported on swine in Guangxi, South China. Results In this study, thirty-three strains detected from 142 E. 116 samples Guangxi 2018. Which...

This study aimed to investigate antibiotic resistance genes in the multidrug-resistant (MDR) Acinetobacter baumannii (A. baumanii) strain, MDR-SHH02, using whole‑genome sequencing (WGS). The antibiotic resistance of MDR-SHH02 isolated from a patient with breast cancer to 19 types of antibiotics was determined using the Kirby‑Bauer method. WGS of MDR-SHH02 was then performed. Following quality c...

We have tested whether tetracyclines (TETs) are able to protect mice from lipopolysaccharide (LPS)-induced shock, a cytokine-mediated inflammatory reaction. Mice, injected with a single dose of tetracycline base (TETb; 1.5, 10 and 20 mg/kg of body weight) or doxycycline (DOXY; 1.5 mg/kg), were significantly protected from a lethal intraperitoneal injection of LPS (500 micrograms per mouse). TET...

Ribosomal protection represents an important tactic for promoting tetracycline resistance in both gram-positive and -negative species. Tet(O) and Tet(M) are the best studied of these determinants and were originally isolated from Campylobacter jejuni and Streptococcus spp., respectively, although both are widely distributed (10). These are the only two ribosomal protection proteins (RPPs) that ...