The present study was initiated to monitor the training load with the magnitude of impact on the hormone concentrations such as testosterone, cortisol and T/C (Testosterone/Cortisol) ratio during the three phases of training (i.e. preparatory, pre-competitive, and competitive phases) in Indian male swimmers preparing for the 2010 Commonwealth Games. Blood samples were collected at the end of ea...

Are hormone levels associated with the attainment of social status? Although endogenous testosterone predicts status-seeking social behaviors, research suggests that the stress hormone cortisol may inhibit testosterone's effects. Thus, individuals with both high testosterone and low cortisol may be especially likely to occupy high-status positions in social hierarchies while individuals with hi...

A 36-year-old transgender man (assigned female at birth) on exogenous testosterone therapy was found to have stage IIA ovarian endometrioid carcinoma, and underwent adjuvant chemotherapy. Diffuse androgen receptor expression in the tumor initiated a multidisciplinary discussion regarding safety of continuing as gender-affirming hormone therapy.

756 VOL 57, NO 11 / NOVEMBER 2008 THE JOURNAL OF FAMILY PRACTICE FAST TRACK Experts recommend a repeat morning testosterone level, plus testing levels of FSH, LH, and prolactin to evaluate the cause of low testosterone Obtain a repeat morning testosterone level, as well as levels of follicle-stimulating hormone (FSH), luteinizing hormone (LH), and prolactin to help understand the cause of low t...

IMPORTANCE OF THE FIELD Heart failure is a progressive disease affecting millions of people worldwide. The disease carries a significantly high morbidity and mortality risk. There are multiple pharmaceutical options to decrease this risk and prolong survival; however, despite optimization of medical management, several patients still await heart transplant, the only definitive cure for heart fa...

introduction: numerous studies have demonstrated that kisspeptin, a peptide from the kiss1 gene, plays an important role in regulating the secretion of gonadotropin releasing hormone (gnrh). also, there is some evidence suggesting that kisspeptin can interact with other neuropeptides for the control of the reproductive axis. in the present study, we have investigated the effect of central admin...

tribulus terrestris is a herbal remedy which is used for various purposes in folk medicine. it has been used as tonic, aphrodisiac, astringent, analgesic, stomachic, anti-hypertensive, diuretic and urinary anti-septic. it is about 30 to 70cm high; it grows as a summer annual, has pinnately compound leaves, yellow flowers and stellate shaped carpel fruits. since the past decades, some plants hav...

Background. Most patients with metastatic prostate cancer are endocrinologically treated with LHRH agonist, but finally castration-refractory and hormone-refractory cancers occur. Serum testosterone levels get low to "the castration level" by LHRH agonists but may not get low enough against castration-refractory prostate cancer. Methods. As case series, twelve patients suffering from hormone-re...

OBJECTIVES This study was designed to measure the beneficial effects of continuous testosterone therapy, delivered by subcutaneous implant, in the relief of somatic, psychological and urogenital symptoms in both pre- and post-menopausal patients, utilizing the validated Health Related Quality of Life (HRQOL), Menopause Rating Scale (MRS). STUDY DESIGN 300 pre- and post-menopausal women with s...

Four male transsexual subjects were given a superactive luteinizing hormone-releasing hormone (LHRH) analogue, D-tryptophan-6-LHRH at daily doses of 100 micrograms for 3--6 mo. A decrease in beard growth, acne, and erectile potency was noted; the latter was documented objectively with the recordings of nocturnal penile tumescence episodes. Plasma testosterone and dihydrotestosterone levels fell...