BACKGROUND Several studies reported that preterm infants were found to be hypersensitive to pain. However, longitudinal and quantitative assessments of subsequent pain thresholds in adolescence are scarce. OBJECTIVE To assess the tenderness threshold in adolescents born prematurely compared with matched children born at full term. DESIGN Case-control study. SETTING Children in the communi...

OBJECTIVE To prepare a tissue engineering approach to fetal membrane repair after premature rupture of the membranes (PROM) by characterizing the proliferation potential of human amnion epithelial and mesenchymal cells from preterm and term placenta in primary culture. METHODS Amnion epithelial and mesenchymal cells from 15 preterm (23-36 week) and 27 term placentas collected at cesarean sect...

BACKGROUND The etiology of persistent lung inflammation in preterm infants with chronic lung disease of prematurity (CLD) is poorly characterized, hampering efforts to stratify prognosis and treatment. Airway macrophages are important innate immune cells with roles in both the induction and resolution of tissue inflammation. OBJECTIVES To investigate airway innate immune cellular phenotypes i...

OBJECTIVES The primary risk factors for necrotizing enterocolitis (NEC) are preterm birth, enteral feeding, and gut colonization. It is unclear whether feeding and colonization induce excessive expression of immune genes that lead to NEC. Using a pig model, we hypothesized that reduced gestational age would upregulate immune-related genes and cause bacterial imbalance after birth. METHODS Pre...

  Background :Preterm birth is a significant global health problem with serious short- and long-term consequences. This study examined the long term effects of preterm birth on vestibular evoked myogenic potentials (VEMPs) among preschool-aged children.   Methods : Thirty-one children with preterm and 20 children with term birth histories aged 5.5 to 6.5 years were studied. Each child underwent...

tested positive for adenovirus. RESULTS: Between January 2005 and December 2006, 193 placenta samples (71 from preterm deliveries and 122 from term deliveries) were collected in Alexandra’s Maternity Hospital in Athens, Greece. The adenoviral genome was isolated in 54 (28%) of 193 placentas. The frequency of adenovirus detection in preterm placentas compared with those from term placentas was s...

conclusions there is no statistically significant relationship between preterm delivery and type of sludge. results the prevalence of preterm delivery was 14/3%. the frequencies of term delivery in mothers with dense, light and no sludge were 78/6%, 82/1% and 96/4 % respectively, and for preterm delivery they were 21/4%, 17/9% and 3/6% respectively. but there was no statistically significant re...

Introduction: This study was designed to compare the plasma lipid peroxidation (LPO) levels in preterm and full-term neonates and their respective mothers, to assess their relationship with the degree of oxidative stress and the levels of vitamin C, an important antioxidant of the body. Material and methods: The studied groups included 70 neonates, 30 preterm (24-36 weeks of gestation) and 40 f...

OBJECTIVE Although cerebellar hemorrhagic injury is increasingly diagnosed in infants who survive premature birth, its long-term neurodevelopmental impact is poorly defined. We sought to delineate the potential role of cerebellar hemorrhagic injury in the long-term disabilities of survivors of prematurity. DESIGN We compared neurodevelopmental outcome in 3 groups of premature infants (N = 86;...

backgroundresistin is reported as an antagonistic hormone of insulin and in the literature. nowadays, importance of resistin is being more highlighted in the metabolism of mother and fetus during pregnancy. this study aimed to assess the level of resistin in the umbilical cord and blood sugar at birth and evaluate the association of resistin and neonatal birth weight.materials and methodsthis c...