نتایج جستجو برای: teriflunomide

تعداد نتایج: 247  

Journal: :Neurology 2014
Lily Jung Henson Steven Cavalier Annette M Langer-Gould

Until fingolimod came along, the first US Food and Drug Administration–approved pill for relapsingremitting multiple sclerosis (RRMS), teratogenicity of multiple sclerosis (MS) drugs had not been a big issue. Strange, for a disease that affects primarily women of childbearing age. Why? Because previously approved MS drugs were all large recombinant protein molecules. Large molecules cross the p...

2009
Clemens Warnke Gerd Meyer zu Hörste Hans-Peter Hartung Olaf Stüve Bernd C Kieseier

In the light of new cases of progressive multifocal leukoencephalopathy and induced autoimmunity in multiple sclerosis (MS) patients who received treatment with upcoming disease-modifying immunosuppressant drugs with a highly specific mode of action such as natalizumab, rituximab, or alemtuzumab, alternative oral treatment options for a subgroup of less severely affected MS patients are a major...

2018
Jacqueline Nicholas Aaron Boster Ning Wu Wei-Shi Yeh Monica Fay Jon Kendter Ming-Yi Huang Andrew Lee

BACKGROUND Data on comparative healthcare resource utilization and costs associated with the newer oral disease-modifying therapies (DMTs) for managing relapsing-remitting multiple sclerosis (MS) in routine clinical practice are limited. The purpose of this study was to estimate healthcare resource utilization, costs, and relapse rates in the year after initiating treatment with dimethyl fumara...

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