The aim of this study was to develop a manufacturing protocol for large-scale production of doped titania radiosensitizing nanoparticles (NPs) to establish their activity under hypoxia and to produce a multimodal radiosensitizing embolic particle for cancer treatment. We have previously shown that radiosensitizing NPs can be synthesized from titania doped with rare earth elements, especially ga...

Background: New treatment modalities are developed with the aim of escalating tumor absorbed dose and simultaneously sparing the normal structures. The use of nanotechnology in cancer treatment offers some possibilities including destroying cancer tumors with minimal damage to healthy tissues. Zinc Oxide nanoparticles (ZnO NPs) are wide band gap semiconductors and seem to have a good effect on ...

A fast, high-spatial-resolution detector for high-energy microscopy work is presented. The detector uses a 2160 x 2560 CMOS chip for fast framing (up to 100 Hz in full-frame mode), coupled by a fiber optic taper to a scintillating Terbium-doped fiber optic plate for excellent stopping power even at high energies. The field of view is 7mm × 8.6mm with a resolution of 9 microns. The sensitivity i...

Ce-doped lanthanum gadolinium pyrosilicate are among the most efficient oxide scintillation crystal with a light yield of ca. 40000 ph./MeV and high energy resolution. Meanwhile, process obtaining...

PURPOSE To develop a simple tissue phantom to study the effects of various imaging parameters and gadolinium concentrations on magnetization transfer (MT) and lesion-to-background ratios. METHODS A commercial egg product was doped with gadolinium in concentrations of 0.0 to 1.0 mmol/L and cooked. The T1 and T2 values were determined for the phantom materials and for the white and gray matter ...

Terbium (Tb) doped zinc oxide (ZnO) thin films were deposited on Si substrates by magnetron sputtering in an oxygen containing plasma. The Tb doping concentration was varied from 0 to 0.38 at.%. effect of heat treatment at high temperature the ultraviolet (UV) emission studied along with structure films. Photoluminescence (PL) spectra show that UV intensity increases much and after 1000 °C anne...

High-density lipoprotein (HDL) nanoparticles doped with gadolinium lipids can be used as magnetic resonance imaging diagnostic agents for atherosclerosis. In this study, HDL nanoparticles with different molar fractions of gadolinium lipids (0 < xGd-lipids < 0.33) were prepared, and the MR relaxivity values (r1 and r2) for all compositions were measured. Both r1 and r2 parameters reached a maxim...

Wide band-gap semiconductors doped with luminescent rare earth elements (REEs) have attracted recent interest due to their unique optical properties. Here we report on the synthesis of the transparent conducting oxides (TCOs) indium oxide and indium tin oxide (ITO) doped with neodymium, europium and terbium. The solid solubility in the systems was investigated and isothermal phase diagrams at 1...