BACKGROUND Scleral cross-linking (CXL) is a novel attempt to slow down the axial elongation process in animal eyes. As a natural CXL reagent, genipin would be also effective for the prevention of myopia process. Thus, the present study was designed to evaluate the effects of scleral cross-linking using genipin on the form-deprivation (FD) myopia process of guinea pigs. METHODS Twenty-seven 3-...

PURPOSE The transdifferentiation of Tenon fibroblasts to myofibroblasts is a pivotal step in filtering bleb scarring. It is mediated by the cytokine TGF-beta, Rho-dependent contractility, and cell-matrix interactions in an interdependent fashion. HMG-CoA-reductase inhibitors (statins) have been shown to inhibit Rho-GTPase signaling; therefore, the authors studied the influence of lovastatin on ...

Muriel Giansily-Blaizot1, Laurie Flory-Pigagniol1, Remi Favier2, Roula A. Farah3, Isabelle Martin-Toutain4, ElisabethVerdy5, Jean-Francois Schved1 1University Hospital Saint Eloi, Laboratory of Haematology, Montpellier, France; 2AP_HP Hospital Armand Trousseau, Laboratory of Haematology, Paris, France; 3Rizk Hospital, Department of Pediatrics, Beirut, Lebanon; 4AP_HP Pitie Salpetriere, Laborato...

Purpose: To evaluate the therapeutic effect of posterior sub-tenon methyl prednisolone in anterior ischemic optic neuropathy, No class 1 study has shown any conclusive medical or surgical treatment for non-arteritic anterior ischemic optic neuropathy (NAION). Efficacy of systemic or intravitreal steroids was suggested by some studies. This study was performed to evaluate the efficacy and safety...

1 Service d’Accueil des Urgences Pédiatrique, Hôpital Robert-Debré-Assistance Publique-Hôpitaux de Paris, Paris, France, 2 Laboratoire de Parasitologie et de Mycologie, Hôpital Pitié-Salpêtrière-Assistance Publique-Hôpitaux de Paris, Paris, France, 3 Service des Maladies Infectieuses et Tropicales, Hôpital Tenon-Assistance Publique-Hôpitaux de Paris, Paris, France, 4 UMR216 “Mère et enfant face...

Department of Pathology, Hôpital Avicenne, AP–HP, Université Paris 13, 93009 Bobigny Cedex, France; Department of Histology, University of Medicine and Pharmacy, Craiova, Romania; URDIA, Service d'Anatomie Biomédicale des Saints Pères, Université Paris 5, 75006 Paris, France; Department of Pulmonary Medicine, Hôpital Avicenne, AP–HP, Université Paris 13, 93009 Bobigny Cedex, France; Laboratory ...

Antoine Badaoui1, Olivier Bayrou1, Charlotte Fite2, Camille Frances1, Angele Soria1,3,4 and Catherine Pecquet1 1Dermatologie-Allergologie, Hôpital Tenon, HUEP, APHP, 75020 Paris, France, 2Dermatologie, Hôpital Bichat, APHP, 75018 Paris, France, 3Unité Mixte de Recherche de Santé (UMR S) CR7, Centre d’Immunologie et des Maladies Infectieuses – Paris (Cimi-Paris), UPMC Université Paris 06, Sorbon...

Structural tests were conducted to determine the strength and deflection characteristics of an 8 by 10 foot light-timber barn frame constructed with 3.5-inch square Douglas-fir members and round mortise and tenon joints. Structural analyses of the frame were also conducted using finite element methods and predicted deflections compared with test values. Results of the tests indicated that the r...