BACKGROUND The most common radionuclide procedures for parathyroid imaging are (99m)Tc-MIBI/ (99m)Tc pertechnetate subtraction scintigraphy and (99m)Tc-MIBI double-phase imaging, with estimation of MIBI wash-out rate. Those two methods are by some authors regarded as complementary techniques, yielding the best evaluation of parathyroid gland if performed conjointly. By such an approach it seems...

Aim: To identify whether the combination of Methoxyisobutylisonitrile (MIBI) and ultrasound scan (USS) in localizing the parathyroid gland preoperatively is more effective than either MIBI or USS alone. Materials and methods: Retrospective manual analysis of patients’ operative and medical notes was undertaken. Patients presenting with raised serum calcium and parathyroid hormone (PTH) between ...

INTRODUCTION Scintigraphy with technetium-sestamibi (MIBI) is the test of choice for localising adenomas in patients with primary hyperparathyroidism (PHPT). In some studies it has emerged that the increase in sensitivity of this test could be associated with a decrease in the uptake of the radiotracer by the thyroid gland. The aim of this study is to analyse our experience in patients with a n...

To compare the role of 99mTc-MIBI SPECT-CT image and US in reoperation of persistent secondary hyperparathyroidism patients. A total of 8 persistent secondary hyperparathyroidism patients underwent parathyroidectomy. The sensitivity and accuracy of US and 99mTc-MIBI images before operation were determined. 9 of 14 surgical resection tissues from 8 persistent secondary hyperparathyroidism patien...

Two cases of brown tumor of the humerus caused by ectopic parathyroid adenomas were presented, which to our knowledge has not been previously documented in the international literature. There are two highlights in these two cases. First, brown tumors of the long bones may commonly involve femur and tibia, rarely involve humerus in association with primary hyperparathyroidism. Second, ectopic pa...

BACKGROUND We investigated a novel technique, intraoperative (99 m)Tc-Sestamibi (MIBI) imaging (neck and excised specimen (ES)), using a large field-of-view portable gamma camera (LFOVGC), for expediting confirmation of MIBI-avid parathyroid adenoma removal. METHODS Twenty patients with MIBI-avid parathyroid adenomas were preoperatively administered MIBI and intraoperatively imaged prior to i...

We use the Hill function to analyze the dynamics of Tc-99m 2 methoxy-isobutyl-isonitrile (Tc-MIBI) scintigraphy data and to examine the earlier lower extremity microvascular perfusion of diabetic patients without typical clinical symptoms and with the preserved normal ankle-brachial index (ABI).Eighty-eight participants (30 healthy control, 34 diabetic patients, and 24 diabetic patients with pe...

UNLABELLED In this study we compared whole body scintigraphy with Tc-99m-methoxyisobutylisonitrile (MIBI) and Iodine-131 NA (131I) for detection of residual and/or metastatic disease in well differentiated thyroid carcinoma. METHODS MIBI and I-131 scans were obtained in 60 patients. TSH measurements were done in all the patients prior to scintigraphy. RESULTS Out of 60 patients, for whom bo...

introduction: we aimed to investigate of effect of left bundle branch block (lbbb) on perfusion and functional parameters in dipyridamole tc99m-mibi gated myocardial perfusion spect which may be helpful in interpretation of myocardial perfusion imaging. methods: we studied 70 patients with low pre-test probability of coronary artery disease in two groups:  35 patients with lbbb and  35 subjects...

UNLABELLED The aim of this study was to assess the value of 99mTc-hexakis2-methoxyisobutylisonitrile (MIBI) scintigraphy in patients with clinical and radiologic features of primary or metastatic musculoskeletal tumors. METHODS The scintigraphic findings for 84 patients were compared with the surgical and histologic findings. Each patient underwent three-phase bone scanning with 99mTc-methyle...