A 2.5-year-old boy with a history of the previous incidental finding of an ectopic kidney in ultrasonography was referred to our nuclear medicine center for 99mTc-DMSA renal scintigraphy. The scan showed an unusual type of ectopic fused kidneys on the right side of the lower abdomen. In this anomaly, kidneys were fused completely across the medial portion of both upper and lower pole...

Urinary tract infections (UTIs) are the most common source of bacterial infections among young febrile children. Accurate diagnosis of acute pyelonephritis (APN) and vesicoureteral reflux (VUR) is important because of their association with renal scarring, leading in the cases to long-term complications. However, the gold standard examinations for both are either DMSA scan (for APN and scar) or...

Introduction:The optimal imaging time of a radionuclide scintigraphy is the time at which the organ of interest has the maximum uptake of the injected radionuclide. This study was performed to investigate the maximum uptake time of 99mTc-DMSA in rat renal scan. Methods: Renal scintigraphy was performed with 3 mCi of 99mTc-DMSA. Planar ima...

INTRODUCTION Urinary tract infections (UTIs) are among the most prevalent infections in children and infants. Early and accurate detection of renal parenchymal involvement in UTI is necessary for decision making and determining treatment strategies. The aim of this study was to determine the predictive accuracy of urinary neutrophil gelatinase-associated lipocalin (NGAL) for renal parenchymal i...

© 2008 Elsevier. All rights reserved. The pentavalent Tc-99m dimercaptosuccinic acid (Tc99m (V) DMSA, Tc(V)-DMSA) radiotracer has become more widely used. The accumulation of Tc(V)-DMSA in tumors was first reported in 1981 [1], and this tracer has subsequently been shown to localize in a variety of tumors [2,3]. Tc(V)-DMSA has also been used to depict abscesses and other inflammatory lesions [4...

the prevalence of vesicoureteral reflux (vur) among siblings of children with vur has been reported to be from 4.7% to 51%. the incidence of vur in the general population is less than 1% but it is high in risk groups. in a prospective study we started identifying the incidence and severity of vur and renal parenchymal lesions in the siblings of patients known to have urinary tract infection (ut...

Renal uptake of 99mTc-DMSA has been quantified by various methods. The aim of this study is to obtain a normal value for 99mTc-DMSA renal uptake calculated by the posterior view method and age variation, and to assess its clinical validity. Scintigrams of 238 children (0-12 years) with 99mTc-DMSA were reviewed. All the children had a clinical history of primary vesicoureteral reflux and/or neur...

Four patients with sonographic suggestion of hepatic hemangioma are studied with Tc99m-labeled RBC scan. The scan findings are compaired with other imaging modalities. Lesions as small as 36 mm could be detected by this method. Tc99m labeled RBC scan is a valuable tool to differentiate hepatic hemangioma from other space occupying lesion of the liver.

AIMS To address some of the issues in the ongoing debate over the optimal diagnostic imaging following childhood urinary tract infection (UTI), by determining the risk of missing renal cortical scarring which would be detected on a technetium-99m dimercaptosuccinic acid (DMSA) gold standard if ultrasound alone were used, factoring for clinical features (upper or lower tract), UTI recurrence, an...