PURPOSE This study aimed to compare the efficacy of two sustained-release formulation of artificial tear drops. PATIENTS AND METHODS This is a randomized patient-masked clinical trial, a total 88 patients into two group A (n=41; with single dose of artificial tear, containing dextran 70, 1mg/ml and hypromellose, 3mg/ml hydroxypropyl methylcellulose (HPMC) and group B (n=47; with multidose of ...

PURPOSE The aim of this study was to evaluate the effect of dietary omega-3 fatty acid (O3FA) supplementation on dry eye symptoms, tear film tests, and conjunctival impression cytology in patients with contact lens wear-associated dry eye. METHODS In this randomized, double-blind, multicentric trial, contact lens wearers (n = 496) were randomized to receive either O3FAs or placebo capsules (c...

this study compared tear function tests and cytologic changes on the conjunctival surface in asymptomatic patients wearing contact lens of different materials. included in this study were 40 eyes wearing daily wear 4 week replacement hydrogel (h) lenses, 32 eyes wearing silicone hydrogel (sih) lenses, 18 eyes wearing rigid gas-permeable (rgp) lenses, and 21 healthy eyes (no lenses) as the contr...

background: artificial tears have been among the first line of therapy in management of dry eye syndrome (des). this study was conducted to compare a local artificial tear with an imported one in reduction of des. this comparison would help to evaluate the cost and benefits of each drop in the proper management of des. m aterials and methods: in this double-blind randomized clinical trial study...

Backgrounds: Computers and gadgets are modern tools for assisting Senior High School students’ work. However, using more than 2 hours a day may cause computer vision syndrome (CVS), which can interfere with academic activities. CVS main symptom is dry eyes. Objectives: could be prevented by applying the 20-20-20 rule artificial tears. Results: A total of 100 students from two public high school...

PURPOSE To evaluate the efficacy of topical cyclosporine A (tCsA) for treatment of dry eye disease in patients suffering from chronic ocular complications of mustard gas (MG) injury. METHODS This interventional case series included patients with MG injury suffering from severe dry eye despite receiving artificial tears and punctal plugs. Patients were administered tCsA 0.05% twice daily for 3...

Purpose. This study aims to explore the safety and efficacy of a novel treatment-intense pulsed light (IPL) in MGD eyes. Methods. This study is a prospective and open label study. Forty eyes of 40 MGD patients were recruited in the study and received 4 consecutive IPL treatments on day 1, day 15, day 45, and day 75. Ten ocular surface symptoms were evaluated with a subjective face score at ever...

OBJECTIVE To determine the frequency of sicca complex, Sjogren's Syndrome (SS) and Fibromyalgia (FM) in patients with Irritable Bowel Syndrome (IBS). METHODS Seventy seven IBS patients who fulfilled the Rome-III criteria were included in the study. All patients were assessed for FM according to the American College of Rheumatology (ACR) 2010 criteria. After examination for objective evidence ...

BACKGROUND Tear lipid morphology is important for normal tear function. Recently, there have been clinical studies using interferometry to assess lipid layer thickness (LLT). The aim of the study is to examine the repeatability of a commercially available interferometer. METHODS Two observers measured LLT in twenty Asian subjects (20 eyes) using an interferometer (LipiView® ocular surface int...