growing evidence suggests that serotonin plays an important role in learning and memory and all its receptors might be implicated in this process. the present study aimed at investigating and comparing the possible involvement of 5-ht 3 and 5-ht 4 receptor (r) agonists/antagonists upon consolidation of inhibitory avoidance memory in the pre-limbic (pl) area. bilateral intra-pl microinjections o...

The "default mode network" is commonly described as a set of brain regions in which activity is suppressed during relatively demanding, or difficult, tasks. But what sort of tasks are these? We review some of the contrasting ways in which a task might be assessed as being difficult, such as error rate, response time, propensity to interfere with performance of other tasks, and requirement for t...

background: memory impairment is a well-known effect of many benzodiazepine compounds which is mediated through their action on gamma-aminobutyric acid type a (gabaa) receptors. on the other hand, cannabinoids can affect learning and memory process through presynaptic modulation of the release of both excitatory glutamate and inhibitory gaba transmitters in brain regions involved in learning an...

RSK2 is a Ser/Thr kinase acting in the Ras/MAPK pathway. Rsk2 gene deficiency leads to the Coffin-Lowry Syndrome, notably characterized by cognitive deficits. We found that mrsk2 knockout mice are unable to associate an aversive stimulus with context in a lithium-induced conditioned place aversion task requiring both high-order cognition and emotional processing. Virally mediated shRNA-RSK2 kno...

Reading is claimed to be the major source of vocabulary growth in L1, but is it also the main source of L2 vocabulary? This paper surveys some experiments in acquiring L2 vocabulary from reading that report very small vocabulary gains from short and long texts. By comparison, reading supplemented with word-focused tasks yields better results. Similarly, when reading is compared with a word-focu...

H1N1 virus is known to affect the respiratory tract. The majority of healthcare providers focus on the respiratory complications attributed to H1N1 infection, overlooking possible multi-organ involvement. We present a rare case of abnormal liver function in a child who was admitted for respiratory illness due to the H1N1 virus. There was a marked elevation in liver function tests concurrent wit...

The interplay of language and cognition in children’s development has been subject to research for a long time. The present study followed up on recently reported deleterious effects of articulatory suppression on children’s executive functioning (Fatzer & Roebers, 2012), aiming to provide more empirical evidence on the differential influence of language on executive functioning. In the present...

background: it has been known that brain-derived neurotrophic factor (bdnf) is involved in neural survival and long term memory (ltm). here we hypothesized that bdnf as a potent neurotrophic factor might modulate amnestic effect induced by morphine. objectives: the aim of this study was to examine whether infusion of exogenous bdnf in the ca1 regions of the dorsal hippocampi could ameliorate me...

Using Spencer-Oatey’s (2004, 2008) Rapport Management approach, this study was conducted to elicit the reprimanding response behavior of native Persian speakers and EFL Learners. The participants of this study were 30 native Persian speakers and 60 EFL learners. To fulfill the purposes of this study, a six-binary situation Interactive Discourse Completion (IDCT) Task was utilized. Emotion Liker...