Habitat loss and fragmentation has created metapopulations where there were once continuous populations. Ecologists and conservation biologists have become interested in the optimal way to manage and conserve such metapopulations. Several authors have considered the effect of patch disturbance and recovery on metapopulation persistence, but almost all such studies assume that every patch is equ...

Abstract AMPA receptor (AMPAR) abundance and positioning at excitatory synapses regulates the strength of transmission. Changes in AMPAR localisation can enact synaptic plasticity, allowing long-term information storage, is therefore tightly controlled. Multiple mechanisms regulating anchoring have been described, but with limited coherence or comparison between reports, our understanding this ...

The recent discovery that vertebrate homologs of Drosophila cornichon associate with AMPA receptors led to the unexpected notion that cornichons play a role in synaptic transmission. In this issue of Neuron, Kato et al. find that cornichons modulate the gating of TARP-associated AMPA receptors by preventing their resensitization to glutamate.