oxytocawithin Hospitals across the United Kingdom and Ireland Identifies Sharing of Virulence and Resistance Genes with K. pneumoniae Danesh Moradigaravand*, Veronique Martin, Sharon J. Peacock, and Julian Parkhill* Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, United Kingdom British Society for Antimicrobial Chemotherapy, Griffin House, Birmingham, United Ki...

BACKGROUND AND OBJECTIVE The association between vitamin D receptor (VDR) gene polymorphisms and the risk of skin diseases has been widely studied, yet there is only one study on atopic dermatitis. In this study, we aimed to investigate the association between 4 VDR polymorphisms and atopic dermatitis. PATIENTS AND METHODS This cross-sectional case control study was performed between March 20...

Vitamin D receptor (VDR) gene variants have been variably associated with risk of colon cancer in epidemiologic studies. We sought to further clarify the relationship between colon cancer and three single-nucleotide polymorphisms (SNPs) in the VDR gene (Cdx-2, FokI and TaqI) in a population-based case-control study of 250 incident cases and 246 controls. Colon cancer cases were more frequently ...

Vitamin D receptor (VDR) gene polymorphisms have been suggested as possible determinants of bone mineral density (BMD) and calcium metabolism. In this study, our aim was to determine whether there is an association between VDR gene polymorphism and osteomalacia or not. We determined ApaI and TaqI polymorphisms in the vitamin D receptor gene in 24 patients with osteomalacia and 25 age-matched he...

The action of a number of restriction enzymes on DNA.RNA hybrids has been examined using hybrids synthesised with RNAs of cucumber mosaic virus as templates. The enzymes EcoRI, HindII, SalI, MspI, HhaI, AluI, TaqI and HaeIII cleaved the DNA strand of the hybrids (and possible also the RNA strand) into specific fragments. For four of these enzymes, HhaI, AluI, TaqI and HaeIII, comparison of the ...

New Zealand Maoris (72 X chromosomes) have been compared with Pacific Island Polynesians (121 X chromosomes) and Caucasian New Zealanders (51 X chromosomes) as a control group to determine the allelic frequency of six RFLPs associated with the genes for two X linked diseases (haemophilia A and haemophilia B). RFLPs examined were BclI, XbaI, and BglI within the factor VIII gene, the factor VIII ...

A study was conducted on genetics of some important agronomic traits (number of productive tillers per hill, plant height (cm), panicle length (cm), number of spikelets per panicle and 100-grain weight) in rice during 2012-13. Two lines were crossed with five testers in line × tester fashion to produce 10 F1 hybrids. Analysis of variance revealed significant differences among genotyp...

A study was conducted on genetics of some important agronomic traits (number of productive tillers per hill, plant height (cm), panicle length (cm), number of spikelets per panicle and 100-grain weight) in rice during 2012-13. Two lines were crossed with five testers in line × tester fashion to produce 10 F1 hybrids. Analysis of variance revealed significant differences among genotyp...

BACKGROUND Over the past 5 years, considerable progress has been made in the identification of polymorphic variation within monoamine system genes that are associated with the attention-deficit hyperactivity disorder (ADHD) phenotype. In this study, we investigated the association of the dopamine D2 receptor (DAD2) TaqI A and ADHD in a Taiwanese sample. METHODS The sample consisted of 98 chil...