Gold(I)-catalysed tandem oxygen-transfer/cycloisomerisation reaction of 2-(2-propynyl)pyridine N-oxides provides an atom-economical route to indolizinone frameworks.

Two series of duplex DNA oligomers were prepared having an anthraquinone derivative (AQ) covalently linked at a 5'-terminus. Irradiation of the AQ at 350 nm leads to injection of an electron hole (radical cation) into the DNA. The radical cation migrates through the DNA causing reaction primarily at G(n) sequences. In one series, GA tandem mispairs are inserted between GG steps to assess the ef...

[reaction: see text] A synthetic approach toward the immunosuppressants SNF3345 C and SNF4435 D featuring a tandem Stille coupling/electrocyclization cascade is described.

Silver(I) triflate efficiently catalyzes the tandem reaction of acetylenic aldehydes with indoles to give highly substituted tetrahydrocarbazoles in high yields.

Starting from conveniently designed dienynes complexed to cobalt, a tandem RCM-intramolecular Pauson-Khand reaction yields tricyclic compounds. The methodology allows the synthesis of 6,5,5 and 7,5,5 systems.

The application of a Pummerer-initiated tandem reaction cascade leads to the highly stereoselective formation of the tetracyclic core of Nakadomarin A.

Correction for 'Triamide macrocyclic chloride receptors via a one-pot tandem reduction-condensation-cyclization reaction' by Harekrushna Behera, et al., Org. Biomol. Chem., 2017, DOI: .

A tandem 1,3-sulfur migration followed by iodocyclization reaction of propargylic sulfides in the presence NIS HFIP has been developed to synthesize indene-based β-iodoalkenyl sulfides. The choice media is crucial promote reaction. proposed mechanism involving initial activation and favoring sulfur starting thioether via cationic intermediates experimentally supported. In addition, suitability ...

A tandem rhodium-catalyzed Bamford-Stevens/Claisen rearrangement is presented. The tandem reaction uses Eschenmoser hydrazones for the in situ generation of non-carbonyl-stabilized diazo alkanes, which are presumably intercepted by Rh(II) catalysts to induce a 1,2-hydride migration. This sequence provides high levels of stereocontrol for the generation of simple acyclic (Z)-enol ethers. These e...

A one-pot three-component synthesis of dihydropyrimidinones via a molecular iodine-catalyzed tandem reaction of simple readily available mono-substituted urea, alkylaldehyde, and arylaldehyde has been developed. The reaction proceeds with high chemo- and regioselectivity to give highly diverse dihydropyrimidinones in reasonable yields under mild reaction conditions. Moreover, the first catalyti...