نتایج جستجو برای: tagged site

تعداد نتایج: 371906  

2017
Edurne Gorraitz Bruce A Hirayama Aviv Paz Ernest M Wright Donald D F Loo

In the human sodium glucose cotransporter (hSGLT1) cycle, the protein undergoes conformational changes where the sugar-binding site alternatively faces the external and internal surfaces. Functional site-directed fluorometry was used to probe the conformational changes at the sugar-binding site. Residues (Y290, T287, H83, and N78) were mutated to cysteines. The mutants were expressed in Xenopus...

Journal: :The Journal of Cell Biology 1999
François Fagotto Eek-hoon Jho Li Zeng Thomas Kurth Thomas Joos Christine Kaufmann Frank Costantini

Axin was identified as a regulator of embryonic axis induction in vertebrates that inhibits the Wnt signal transduction pathway. Epistasis experiments in frog embryos indicated that Axin functioned downstream of glycogen synthase kinase 3beta (GSK3beta) and upstream of beta-catenin, and subsequent studies showed that Axin is part of a complex including these two proteins and adenomatous polypos...

2001
Wendy D. Manning

Children are increasingly part of cohabiting unions. The marriage literature indicates that children generally promote stability of marriages but it remains unknown whether children have a similar effect on the stability of their parent’s cohabiting unions. Using the National Survey of Family Growth this paper evaluates the effects of children on the stability of cohabitation. This paper expand...

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