نتایج جستجو برای: tableting

تعداد نتایج: 232  

2011
A Raman QINGNAN ZHANG Qingnan Zhang

The purpose of this work is to investigate the relation of hydration and the degree of crystallinity for poly (ethylene oxide) (PEO) tablets using Raman spectroscopic methods and complementary thermal analysis for pharmaceutical interests. The influence of the tableting process is also investigated by measuring the degree of crystallinity and the melting point of PEO powder and tablets. The hyd...

2012
Eduardo Costa Pinto Flávia Almada do Carmo Thiago da Silva Honório Rita de Cássia da Silva Ascenção Barros Helena Carla Rangel Castro Carlos Rangel Rodrigues Valéria Sant'Anna Dantas Esteves Helvécio Vinícius Antunes Rocha Valeria Pereira de Sousa Lucio Mendes Cabral

The purpose of this study was to propose an analytical procedure that provides the effects of particle size and surface area on dissolution of efavirenz. Five different batches obtained by different micronization processes and with different particle size distribution and surface area were studied. The preformulation studies and dissolution curves were used to confirm the particle size distribu...

Journal: :International Journal of Pharmaceutics 2021

The mechanical properties of powders determine the ease manufacture and ultimately quality oral solid dosage forms. Although poor an active pharmaceutical ingredient (API) can be mitigated by using suitable excipients in a formulation, effectiveness that approach is limited for high dose drugs or multidrug tablets. In this context, improving APIs through form optimisation good strategy to addre...

Journal: :Powder Technology 2022

In this study, the question of how fragmentation and deformation granules during compression can be linked to tableting performance dry granulated powders is addressed. Granulated a systematically varied composition plastic brittle material were prepared by slugging thereafter compacted into tablets. The tablet's micro-structure, porosity, tensile strength assessed; moreover, relationships betw...

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