corticosteroid resistant and dependent nephrotic syndrome in children is a challenge and there are some difficulties in treating such patients. we reviewed the current studies that evaluated therapeutic role of a relatively new immunosuppressive drug “rituximab” in reducing proteinuria and reduction of relapse rate in less than 16 year old patients with non-responsive or steroid dependent nephr...

there has been too much of a one-way flow drift down a river of evidence. researchers from rich countries have produced the primary evidence which they proceed to summarise within reviews. these summaries have directed care worldwide. however, things are changing and the river of evidence can flow in the other direction. the care of women with eclampsia has been changed or refined throughout th...

background: breast cancer is the most common cancer in women worldwide. recently, natural remedies such as naringenin (nar) - a kind of flavonoids which can be found in grapefruits, oranges, and tomatoes - seem to be interesting. they play a useful role in treatment and chemoprevention because of having pleiotropic molecular mechanisms of action on breast cancer cells. methods: we performed a p...

inappropriate use of drugs is a widespread problem with serious consequences such as increased adverse drug reaction and antimicrobial resistance. proper interventions would have important financial and public health benefits. several studies have been performed about rational drug use (rud) in iran. to provide a picture of researches were done about rud and highlight the existing gaps in pract...

conclusions the majority of iranian women had neutral attitudes towards menopause, which may be evidence of poor knowledge about menopause. therefore, it is suggested that appropriate educational programs be developed and implemented by policymakers in order to increase knowledge and raise awareness among women about menopause. results out of the 21 selected documents, 11 studies were eligible ...

background & aim : the number of cancer patients has been continuously increasing due to early diagnosis and the developments in cancer treatment. this has led to an increase in psychosocial problems associated with the diagnoses and treatment of cancer. loneliness is emphasized to be one of the most frequently observed psychological symptoms in cancer patients. personal and external factors th...

background: the most common symptoms experienced by women are hot flashes are around the time of menopause. many women are interested in herbal medicines because of fear of side effect of hormone therapy. objective: in this study, we seek to assess the effectiveness of herbal medicine on the recurrence of hot flash in menopausal women. methods: the database of medline, scopus, and the cochrane ...

introduction: in recent years, a few studies have been conducted in the area of the cost-effectiveness of the eplerenone; it's notable that coherent and clear evidence are not available. therefore, this study aimed to systematically review studies of cost-effectiveness of eplerenone in the treatment of cardio-vascular patients. methods: this systematic review study was conducted in 2016. t...

background: there is a great deal of descriptive studies on obesity in iran, mostly assessed the prevalence and its relation­ship with various risk factors and chronic diseases. in order to obtain/give a better insight into the epidemiology of obesity in iran in recent years and assess its heterogeneity around the country, we reviewed systematically all available studies and ana­lyzed their fin...