objective(s): gallium‐68 (ga‐68) is an ideal research and hospital‐based pet radioisotope. currently, the main form of ga‐68 radiopharmaceutical that is being synthesised in‐house is ga‐68 conjugated with dota based derivatives. the development of automated synthesis systems has increased the reliability, reproducibility and safety of radiopharmaceutical productions. here we report on our three...

The SiO2-CaCl2 hybrid porous materials were prepared by the sol-gel method. This process was conducted by the hydrolysis and condensation of Tetraethyl orthosilicate (TEOS) by replacement of ethanol from alcogel and drying at the ambient temperature to obtain xerogel structure. The alcogel samples were synthesized from TEOS, EtOH, H2O, HCl, NH4OH and CaCl2, while the total molar ratio of the co...

silver is composed of a large percentage of silver oxide due to their large ratio of surface to bulk silver atoms. silver nanoparticles have been a potent antibacterial, antifungal, anti-viral and anti-inflammatory agent. a simple, eco-friendly, inexpensive biosynthetic method was employed to synthesize silver nanoparticles.  the present study aimed at the comparative study of silver nanopartic...

in the present study, a heterogeneous and homogeneous gas flow dispersion model for simulation and optimization of a large-scale catalytic slurry reactor for the direct synthesis of dimethyl ether (dme) from synthesis gas (syngas) and co2, using a churn-turbulent regime was developed. in the heterogeneous flow model, the gas phase was distributed into two bubble phases including small and large...

the present study aimed to use a method for the synthesis of some 3, 4-dihydropyrimidin-2-(1h) - ones/thiones. the study tried to answer the question whether this reaction can be performed without solvent and with new catalyst or not. to find answer to the question, we described a novel protocol for the efficient synthesis of 3, 4-dihydropyrimidin-2-(1h)-one derivatives using aromatic aldehyde,...

For current gene synthesis protocols, usually a set of individually designed single-stranded oligonucleotides is first constructed using automated solid-phase synthesisers. Then the oligonucleotides are purified and subsequently assembled using specific annealing and standard ligation or polymerase reactions. To improve specificity of oligonucleotide annealing, the synthesis step relies on a se...

a one-pot synthesis of (s)-(-)-propranolol is reported. zn(no3)2/(+)-tartaric acid catalyzed enantioselective synthesis of (s)-(-)-propranolol via kinetic resolution of key intermediate ?-naphthyl glycidyl ether with high optical and chemical yield.