نتایج جستجو برای: synergistic effect

تعداد نتایج: 1664483  

Journal: :Journal of Carcinogenesis 2008
Neelu Puri Ravi Salgia

BACKGROUND c-Met and EGFR receptors are widely expressed on cancer cells; they are implicated in the development and progression of cancer through a plethora of effects on cell cycle progression, apoptosis, motility and metastasis and are potential targets for combination therapy. EGFR receptor tyrosine kinases are currently being targeted in a number of malignancies. METHODS Apoptosis was st...

2011
Yongping Liu Yang Ling Wenjing Hu Li Xie Lixia Yu Xiaoping Qian Binxia Zhang Baorui Liu

The herb medicine formula "Chong Lou Fu Fang" (CLFF) has efficacy in inhibiting the proliferation of human gastric cancer in vitro and in vivo. To explore the potentially useful combination of CLFF with chemotherapeutic agents commonly used in gastric cancer therapy, we assess the interaction between CLFF and these chemotherapeutic agents in both SGC-7901 cell lines and BGC-823 cell lines using...

We studied the antioxidant activities of the essential oils of Zataria multiflora Boiss. (ZEO) and Bunium persicum (Boiss.) B. Fedtsch (BEO) in mixed form on linseed oil using (DPPH•), ­(­ABTS•+), H2O2 scavenging, and reducing power assays. After calculation of IC50 for ZEO and BEO separately, interactions of the essential oils were investigated at the form of mixture and the results were given...

Journal: :ACS nano 2015
Sijie Wan Yuchen Li Jingsong Peng Han Hu Qunfeng Cheng Lei Jiang

Inspired by the ternary structure of natural nacre, robust ternary artificial nacre is constructed through synergistic toughening of graphene oxide (GO) and molybdenum disulfide (MoS2) nanosheets via a vacuum-assisted filtration self-assembly process. The synergistic toughening effect from high mechanical properties of GO and lubrication of MoS2 nanosheets is successfully demonstrated. Meanwhil...

2011
Valentina Zuco Michelandrea De Cesare Raffaella Cincinelli Raffaella Nannei Claudio Pisano Nadia Zaffaroni Franco Zunino

Preclinical studies support the therapeutic potential of histone deacetylases inhibitors (HDACi) in combination with taxanes. The efficacy of combination has been mainly ascribed to a cooperative effect on microtubule stabilization following tubulin acetylation. In the present study we investigated the effect of paclitaxel in combination with two novel HDACi, ST2782 or ST3595, able to induce p5...

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Background: The efficacy of glutamine and Curcumin consumption and their synergistic effect on muscle damage recovery over five days is not clear yet. The purpose of this study was to compare the effect of these two supplements and their synergistic effect on serum markers of muscle damage and muscular pain perception after an eccentric exercise session. Methods: Forty non-athlete young men we...

A series of copper and cobalt substituted nanospinel ferrites have been synthesized by the hydrothermal method. These compounds were characterized by FT-IR, XRD, EDX, SEM and VSM techniques. All of the synthesized nanospinel ferrites were found to be highly efficient and magnetically recoverable in the solvent-free synthesis of substituted 2,6-(2-hydroxybenzyl)-phenols (trisphenols). A wide ran...

2014
Nina Cedergreen

Cocktail effects and synergistic interactions of chemicals in mixtures are an area of great concern to both the public and regulatory authorities. The main concern is whether some chemicals can enhance the effect of other chemicals, so that they jointly exert a larger effect than predicted. This phenomenon is called synergy. Here we present a review of the scientific literature on three main gr...

2017
Suman Kumari Hitesh Kumar Preeti Jain

Objective: To evaluate the synergistic effect of antimicrobial plant extracts from traditional medicinal plants on standard microorganism strains. Method: In the present study, eight plants (extracted with five different solvents) were screened for antibacterial activity against four gram negative and four gram positive strains by micro-broth dilution assay. Afterward, antimicrobial chloroform ...

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