By Chikamasa Ninagawa (蜷川 親 正) From the Department of Physiology, Nagasaki University School of Medicine, Nagasaki (Received for publication, July 20, 1955) It is not long since the evidences of secretion in the plantar sweat glands of rats were given. Ring and Randall1) were the first to study histologically the plantar sweat glands in rats. Further, they found that the sweating was causable b...

Muscle cramps may be caused by fluid and salt loss induced by diffuse or focal hyperhidrosis. Recent reports have described the efficacy of botulinum, toxin in the treatment of primary focal hyperhidrosis. Botulinum toxin inhibits sweating by blocking exocytosis of acetylcholine from presynaptic cholinergic nerve terminals. We report the case of a patient who complained of frequent muscle cramp...

Background: Primary hyperhidrosis is a sympathetic disorder characterized by prolonged and uncontrollable sweating. It associated with emotional stress or psychological causes that preferably affects the axillae, palms, feet, face. Video-assisted thoracoscopic surgery currently globally recognized treatment for primary palmar (PH). However, compensatory sweating (CS) most prominent long-term ad...

Thermal manikins are essential tools for the comfort evaluation of the thermal environment and clothing as well as research into the dynamics of heat and moisture transfer from the human body to the environment – a foundation for thermal physiology and environmental engineering. Since the development of the first non-sweating, single segment copper thermal manikin by the US Army in 1940s, there...

OBJECTIVES This case report aims to help healthcare providers and methadone clinic patients to recognize one of the less recognized adverse effects of methadone, hyperhidrosis, and to suggest oxybutynin as a possible solution. METHODS A 35-year-old man on methadone maintenance therapy presented with excessive sweating, which began promptly after methadone was introduced. Urine toxicology was ...

One of the objectives of the European SUBZERO project was to study the influence of sweat evaporation and condensation on the heat transmission properties of cold protective clothing. With the sweating thermal manikin Coppelius, water vapour transfer through and water condensation in the clothing can be determined simultaneously with the thermal insulation. In this study, 4 cold protective ense...

A woman was isozygous for a novel mutation in the leukemia inhibitory factor receptor gene (LIFR) (c.2170C>G; p.Pro724Ala) which disrupts LIFR downstream signaling and results in Stüve-Wiedemann syndrome (STWS). She inherited two identical chromosomes 5 from her mother, heterozygous for the LIFR mutation. The presentation was typical for STWS, except there was no long bone dysplasia. Prominent ...