RATIONALE Smoking-induced chronic obstructive pulmonary disease (COPD) is associated with acquired systemic cystic fibrosis transmembrane conductance regulator (CFTR) dysfunction. Recently, sweat evaporimetry has been shown to efficiently measure β-adrenergic sweat rate and specifically quantify CFTR function in the secretory coil of the sweat gland. OBJECTIVES To evaluate the presence and se...

We present the findings of an early-stage primary mucinous sweat gland adenocarcinoma in the lower eyelid of a Japanese patient. The patient was a 73-year-old man who had had a nodule on the left lower eyelid for two years. He was referred to our hospital with a diagnosis of a swollen chalazion. The clinical and histopathological records were reviewed and the mass was excised. Histopathological...

Sweat gland carcinomas are rare skin tumors that typically occur in older patients. The spectrum of their clinical and pathologic features is broad, and many different types of sweat gland carcinomas have been described, ranging from fairly indolent to highly aggressive neoplasms. We present two cases of sweat gland carcinoma with a predominant small cell morphology. Both tumors occurred in chi...

Human skin harbours multiple different stem cell populations. In contrast to the relatively well-characterized niches of epidermal and hair follicle stem cells, the localization and niches of stem cells in other human skin compartments are as yet insufficiently investigated. Previously, we had shown in a pilot study that human sweat gland stroma contains Nestin-positive stem cells. Isolated swe...

SAW, KENZO. Sweat induction from an isolated eccrine sweat gland. Am. J. Physiol. 225(5) : 1147-l 152. 1973.-A method has been developed for in vitro induction of sweating from an isolated monkey-palm eccrine sweat gland. The validity of the new methodology is shown in the following results. MecholyLinduced sweating was completely inhibited by atropine and by cooling the incubation medium to 4 ...

Eccrine porocarcinoma is a rare malignant adnexal tumor of ductal portion of eccrine sweat gland. It occurs commonly in the lower extremities and rarely in scalp, face, ear, trunk and upper extremities. This survey presents a classic case of eccrine porocarcinoma of scalp in a 58 yr old male patient, presenting as cauliflower like growth over parietal aspect of scalp.  

BACKGROUND Patients with familial dysautonomia (FD) manifest episodic hyperhidrosis despite the reduction of sudomotor fibres and sweat glands associated with this autonomic neuropathy. We assessed peripheral sudomotor nerve fibre and sweat gland function to determine if this symptom was due to peripheral denervation hypersensitivity. METHODS In 14 FD patients and 11 healthy controls, direct ...

OBJECTIVE To review possible peculiarities in biological mechanisms related to responses of thermoregulatory and specific sweat glands in exercise performed by children in hot environments. DATA SOURCES Review of 47 articles published between 1960 and 2011 in the electronic databases MedLine and SciELO Brazil using the following key-words: 'children', 'heat', 'sweating', 'thermoregulation', '...

Effects of local skin temperature on sweat gland activity were analyzed quantitatively by measuring changes in the rates of thermal sweating and of drug-induced sweating by local heating. The data indicates that a rise in local temperature causes an accelerated increase in the rate of sweat production, the Q10 being around 2.5 regardless of the basal sweat rate with some individual variations. ...

Cutaneous sweat gland carcinoma is an extremely rare malignant skin cancer which may arise from the apocrine or eccrine types of glands. It has a high mitotic index and potential [1] usually occurs in elderly people, without any gender predilection.