نتایج جستجو برای: survivin promoter

تعداد نتایج: 93691  

2016
Aurelie Bedel François Beliveau Isabelle Lamrissi‐Garcia Benoit Rousseau Isabelle Moranvillier Benoit Rucheton Veronique Guyonnet‐Dupérat Bruno Cardinaud Hubert de Verneuil François Moreau‐Gaudry Sandrine Dabernat

: Iatrogenic tumorigenesis is a major limitation for the use of human induced pluripotent stem cells (hiPSCs) in hematology. The teratoma risk comes from the persistence of hiPSCs in differentiated cell populations. Our goal was to evaluate the best system to purge residual hiPSCs before graft without compromising hematopoietic repopulation capability. Teratoma risk after systemic injection of ...

Journal: :European Journal of Cancer 2022

Background: Survivin is a member of the Inhibitor Apoptosis (IAP) protein family, and involved in regulation cell division inhibition apoptosis. Although survivin not expressed most normal human tissues, it has shown to be upregulated many cancers, including esophageal cancer. Based on its differential expression malignant tissues critical role regulating survival, an attractive candidate for t...

Journal: :مجله دانشگاه علوم پزشکی کردستان 0
کیهانه کیانی keihaneh kiani genetics dept., school of medicine, islamic azad university, najafabad branch, isfahan, iranگروه ژنتیک، دانشگاه آزاد اسلامی، واحد نجف آباد، نجف آباد، ایران محمد علی حسین پور فیضی mohammad ali hosseinpour feizi animal biology dept., school of natural sciences, university of tabriz, tabriz, iranگروه زیست شناسی جانوری، دانشگاه تبریز، تبریز، ایران اسماعیل بابائی esmail babaie genetics, dept. of animal biology, school of natural sciences, university of tabriz, tabriz-iranگروه زیست شناسی جانوری، دانشکده علوم طبیعی، دانشگاه تبریز، تبریز، ایران وحید منتظری vahid montazeri thorax surgery dept., tabriz university of medical science, tabriz, iranگروه جراحی، دانشگاه علوم پزشکی تبریز، تبریز، ایران منیره حلیمی monireh halimi pathology dept., tabriz university of medical science, tabriz, iranگروه پاتولوژی، دانشگاه علوم پزشکی تبریز، تبریز، ایران

abstract background and aim: survivin is a new member of inhibitor of apoptosis protein family (iap) that plays an important role in the regulation of cell cycle and inhibition of apoptosis. distinct expression of this gene in tumoral cells versus normal cells introduces it as the fourth major transcriptome in cancers. thyroid carcinoma is the most common endocrine malignancy. considering the h...

صالح نیا, مژده, مازوچی, طاهره, خامه چیان, طاهره ,

Introduction & Objective: Survivin is one of the new characterized members of the inhibitor of apoptosis proteins that shows widespread expression in embryonic and tumoric tissues. The aim of this study was to evaluate the expression of Survivin variants in different stages of follicular development in mouse ovary. Materials & Methods: This experimental study was carried out on immature fema...

2012
Xin-Ran Liu Ying Cai Xin Cao Rui-Cheng Wei Hui-Ling Li Xiu-Mei Zhou Kang-Jian Zhang Shuai Wu Qi-Jun Qian Biao Cheng Kun Huang Xin-Yuan Liu

Cancer Targeting Gene-Viro-Therapy (CTGVT) is a promising cancer therapeutical strategy that strengthens the anti-tumour effect of oncolytic virus by expressing inserted foreign anti-tumour genes. In this work, we constructed a novel adenoviral vector controlled by the tumour-specific survivin promoter on the basis of the ZD55 vector, which is an E1B55KD gene deleted vector we previously constr...

Journal: :Biochemical and biophysical research communications 2006
Fumiaki Sato John M Abraham Jing Yin Takatsugu Kan Tetsuo Ito Yuriko Mori James P Hamilton Zhe Jin Yulan Cheng Bogdan Paun Agnes T Berki Suna Wang Yutaka Shimada Stephen J Meltzer

For developing successful cancer gene therapy strategies, tumor-specific gene delivery is essential. In this study, we used esophageal cancer (EC) cells to identify and evaluate esophageal tumor-specific gene promoters. Four genes (polo-like kinase-1/PLK, survivin/BIRC5, karyopherin alpha 2/KPNA2, and pituitary tumor transforming gene protein 1/PTTG1) were identified by a microarray analysis as...

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