BACKGROUND Surrogacy is a highly debated method mainly used for treating women with infertility caused by uterine factors. This systematic review summarizes current levels of knowledge of the obstetric, medical and psychological outcomes for the surrogate mothers, the intended parents and children born as a result of surrogacy. METHODS PubMed, Cochrane and Embase databases up to February 2015...

BACKGROUND The new method described here is highly efficient in transferring microinjected mouse eggs (MEs) through the bursa membrane of a surrogate mother mouse to the ampulla of the oviduct without damaging the blood vessels on the bursa membrane. RESULTS This method causes no loss of blood, and it produces newborn pups/founders from approximately 70% of the transferred MEs, because only a...

OBJECTIVE Early life events often lead to deficits in CNS serotonin function, which underlie a number of reoccurring psychopathological disorders. Studies using rhesus macaques have demonstrated that early maternal deprivation reduces CNS serotonin turnover, as measured by cisternal CSF 5-HIAA concentrations. In addition, individual differences in CSF 5-HIAA remain stable from the first year of...

Knowledge of the characteristics of family structure may be helpful to the pediatrician for predicting child abuse. During the past several decades progressive shifts from the classic family unit of two biological parents and their children to a variety of parental living arrangements have occurred. Most notable are the increases in teenage pregnancies, unmarried motherhood, divorce rates appro...

The challenge of the case presented was threefold: congenital absent uterus (Mayer-Rokitansky-KustnerHauser syndrome), a request for surrogacy, and teratozoospermia in the husband (6% normal morphology according to the Tygerberg strict criteria). Surrogacy was dealt with by means of guidelines proposed by the SA Law Commission after a surrogate mother was found. The gestational carrier was sync...

BACKGROUND/AIM Obtaining human embryonic stem cell lines has so far involved destroying the embryos. This has given rise to ethical concerns and is not permitted in most countries. This investigation tested whether removing multiple cells from blastocysts might allow continued embryonic development. MATERIALS AND METHODS A total of 40 blastocysts from a black mouse strain were biopsied. The m...

STUDY QUESTION What impact does surrogacy have on the surrogates' own children? SUMMARY ANSWER The children of surrogate mothers do not experience any negative consequences as a result of their mother's decision to be a surrogate, irrespective of whether or not the surrogate uses her own egg. STUDY DESIGN, SIZE AND DURATION Participants were recruited as part of a study of the long-term eff...

Background: Several methods for sex selection of embryos have been used in research centers and infertility centers till now. Materials and Methods: In this research, the effect of medium, by placing the mouse (NMRI) spermatozoa in the medium containing certain concentrations of albumin and ascorbic acid, separation of spermatozoa containing X and Y chromosomes and doing in vitro fertilization ...