نتایج جستجو برای: suppressive therapy
تعداد نتایج: 665551 فیلتر نتایج به سال:
Background: Malaria treatment in Africa is increasingly becoming difficult resulting from Plasmodium falciparum resistant to available antimalarial agents. Therefore, evaluating plants used traditional medicines can lead alternative against malaria.Methods: This study evaluated the antiplasmodial activity of ethanol extract Dacryodes edulis chloroquine sensitive berghei NK65 strain mice. The 4-...
BACKGROUND Characterising the correlates of HIV persistence improves understanding of disease pathogenesis and guides the design of curative strategies. This study investigated factors associated with integrated HIV-1 DNA load during consistently suppressive first-line antiretroviral therapy (ART). METHOD Total, integrated, and 2-long terminal repeats (LTR) circular HIV-1 DNA, residual plasma...
Background Neonatal herpes is a potentially devastating infection that results from acquisition of herpes simplex virus (HSV) type 1 or 2 from the maternal genital tract at the time of vaginal delivery. Current guidelines recommend (1) cesarean delivery if maternal genital HSV lesions are present at the time of labor and (2) antiviral suppressive therapy for women with known genital herpes to d...
BACKGROUND Epidemiologic data suggest that infection with herpes simplex virus type 2 (HSV-2) is associated with increased genital shedding of human immunodeficiency virus type 1 (HIV-1) RNA and HIV-1 transmissibility. METHODS We conducted a randomized, double-blind, placebo-controlled trial of HSV suppressive therapy with valacyclovir (at a dose of 500 mg twice daily) in Burkina Faso among w...
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