To the Editor In a randomized clinical trial, Dr Foa and colleagues examined prolonged exposure psychotherapy for co-occurring posttraumatic stress disorder (PTSD) and alcohol dependence. Prolonged exposure therapy was studied in relation to supportive counseling, use of naltrexone, and a pill placebo. The article provides an example of how the same findings can be interpreted quite differently...

Fenton WS: Evolving perspectives on individual psychotherapy for schizophrenia. Schizophrenia Bulletin 2000; 26(1):47–72 Summary: This article provides a history of theory about individual psychotherapy for schizophrenia as well as a literature review of randomized clinical trials that have evaluated individual psychotherapy of schizophrenia. The authors note that the most common treatment for ...

OBJECTIVES To determine whether maintenance antidepressant pharmacotherapy and interpersonal psychotherapy sustain gains in health-related quality of life (HR-QOL) achieved during short-term treatment in older patients with depression. DESIGN After open combined treatment with paroxetine and interpersonal psychotherapy, responders were randomly assigned to a two (paroxetine vs placebo) by two...

BACKGROUND Changes in serum concentrations of tumor necrosis factor-α (TNF-α) and its soluble receptors (sTNF-R) p55 and p75 have been shown to be associated with various psychiatric treatments. SUBJECTS AND METHODS Before and after treatment, serum levels of TNF-α, sTNF-R p55 and sTNF-R p75 were measured in 38 German soldiers who had been deployed abroad and suffered from combat-related post...

BACKGROUND Minimal efficacy differences have been found between cognitive behavioral therapy (CBT) and psychodynamic therapies for depression, but little is known about patient characteristics that might moderate differential treatment effects. We aimed to generate hypotheses regarding such potential prescriptive factors. METHOD We conducted post-hoc model-based recursive partitioning analyse...

Introduction As reported by the editor of The Forensic ~ c h o , ' the number of applicants to the many forensic psychiatry training programs in this country has increased sharply. With the expanding corrections economy, "a bright idealistic generation" now has an opportunity to work with the "underbelly of society." It is at last possible to acknowledge openly that "Not every prisoner with a p...

If psychoanalytic treatment is to survive in the era of evidence-based medicine and managed care systems, empirical evidence is needed to demonstrate its unique nature and effectiveness. To address this need, comprehensive analyses were conducted of data from the Menninger Psychotherapy Research Project (Wallerstein 1986). These analyses addressed three questions: (1) What are the differences i...

OBJECTIVE This study tested the efficacy of a new psychotherapy, flexible coping psychotherapy (FCP), specifically designed for enhancing coping flexibility of patients with functional dyspepsia (FD). The design of this psychotherapy is based on the general cognitive-behavioral model and previous findings on FD. METHODS We adopted a randomized, controlled design to examine the differences bet...