Superficial fungal infections are caused by dermatophytes plus candida and pityrosporum yeasts. Dermatophytosis is usually classified clinically according to the site of involvement: tinea capitis (scalp), T. corporis (body), T. cruris (groin), T. pedis (feet) and T. unguium (nails). One-half of all the cases of T. capitis and T. corporis are caused by zoophilic fungi, the rest due to anthropop...

OBJECTIVE The use of antifungal prophylaxis remains controversial in most populations including surgical intensive care unit patients. A meta-analysis of randomized controlled trials was performed to evaluate the safety and effectiveness of azoles as antifungal prophylaxis in high-risk patients receiving treatment in the surgical intensive care unit. DATA SOURCE Data were obtained from PubMed...

Superficial fungal infections are among the most common dermatological conditions encountered. Current diagnostic tests include direct microscopic examination, followed by conventional culture. Fungal culture is time consuming, with an inherent risk of false negative results. The advent molecular diagnostics potentially allows faster and more sensitive methods testing. This study aims to evalua...

Onychomycosis is a common infection of the nail plate caused by fungal microrganisms, and represents approximately 50% of nails disorders and 30% of all superficial mycotic infections. We present a study of the frequency, epidemiology and clinical aspects of onychomycosis in the central region of Rio Grande do Sul during the period 1988-1997.

Miconazole, a parenterally administered imidazole antifungal agent has been shown to produce responses in systemic fungal infections in man. Ketoconazole, an analogue, can be given by mouth. It is inhibitory in vitro at low concentrations to most fungi. Blood levels after oral administration to animals and man greatly exceed these inhibitory concentrations for several hours. The efficacy of thi...

The risk for invasive fungal infections in patients with acute leukemia is generally low (4%–8%), and the routine use of fungal prophylaxis is not warranted except in specific high-risk groups that should be identified among this population. In a prophylactic study with a new agent, fluconazole or itraconazole oral solution represent good choices for the comparator because they are proven bette...

Candida albicans is a medically important fungus that can cause a wide range of diseases ranging from superficial infections to disseminated disease, which manifests primarily in immuno-compromised individuals. Despite the currently applied anti-fungal therapies, both mortality and morbidity caused by this human pathogenic fungus are still unacceptably high. Therefore new prophylactic and thera...

Submit Manuscript | http://medcraveonline.com Superficial fungal infections of the skin, hair, and nails are dermatomycoses that affect the individuals’ health quality of life and are considered a public health issue [1-3]. Dermatological infections affect more than 25% of the people worldwide living in tropical and subtropical regions, mainly individuals involved in outdoor activities, such as...

The common dermatophyte genera Trichophyton, Microsporum, and Epidermophyton are major causes of superficial fungal infections in children. These infections (e.g., tinea corporis, pedis, cruris, and unguium) are typically acquired directly from contact with infected humans or animals or indirectly from exposure to contaminated soil or fomites. A diagnosis usually can be made with a focused hist...