Treatment with amiodarone, a commonly prescribed antidysrhythmic agent, is associated with pulmonary fibrosis (PF) which is a commonly progressive and untreatable disease. Caffeic acid phenethyl ester (CAPE) is a phenolic antioxidant and an active anti-inflammatory , anticancer, antimicrobial and antioxidant component of propolis (bee glue; a resinous hive product collected by honey bees). In t...

Objective: The current study was planned to investigate the anti-carcinogenic & anti-oxidant property of Ruellia tuberosa L. (Acanthaceae) methanolic leaf extract (MERTL) on HepG2 cell line & RAW 264.7 murine macrophage cell lysate respectively. Methods: The potent cytotoxic activity of MERTL has been studied by cell growth inhibition study & MTT assay on metabolically active HepG2 cells. 1% Ag...

Oxidative Stress is implicated as one of the primary factors that contribute to the development of neurodegenerative diseases like Alzheimer's Disease, Parkinsonism and neurological conditions like epileptic seizures, stroke, brain damage, neurotrauma etc. The increased formation and release of oxygen free radicals coupled with the rather low antioxidative potential of the central nervous syste...

doxorubicin (dox) induces oxidative stress leading to cardiovascular abnormalities. green tea extract (gte) is reported to possess antioxidant activity mainly by means of its polyphenolic constituent, catechins. our study was aimed to find out the effect of gte (100 mg/kg / day p.o. for 28 days) on dox induced (3 mg/kg, ip on days 1, 7, 14, 21, 28) cardiovascular abnormalities in rat heart. dox...

BACKGROUND Reduced arterial compliance is associated with an increased rate of morbidity and mortality in cardiovascular disease. Exercise is beneficial for compromised arterial compliance. However, the beneficial effects of exercise are lost with exhaustion. Lycium barbarum L. has been used in China for centuries to maintain good health. In this regard, the primary purpose of this study was to...

3 Robert Meller, D.Phil., Roger P. Simon, MD 2 4 5 Translational Stroke Program, Neuroscience Institute, Morehouse School of Medicine, 6 Grady Memorial Hospital, Atlanta, GA USA 7 8 Running Title: Mechanisms of remote preconditioning 9 10 Correspondence: Robert Meller, Neuroscience Institute, Morehouse School of 11 Medicine, 720 Westview Dr SW, Atlanta, 30310. Tele 4047565789: Email 12 rmeller@...