Results: The rate of bacteriuria was found statistically higher in 50 patients under trimethoprim/sulphamethoxazole and 17 under nitrofurantoin prophylaxis after the urodynamics (P < 0.05) compared to pre-urodynamics. According to our results, the most frequently bacteria detected before urodynamic testing was E. coli (in 25 patients, 3 of them ESBL + strains) as it was the same as post-urodyna...

A 42-year-old patient was successfully treated for subacute bacterial endocarditis due to Esch. coli with oral trimethoprim and sulphamethoxazole. The treatment lasted nine months and was continued through a period of cholestatic jaundice superimposed on hepatic damage due to subacute bacterial endocarditis. There were no toxic effects attributable to the two antibacterials despite their prolon...

In this study, new derivatives of pyrazole, isoxazole, pyrazolylthiazole, and azolopyrimidine having a thiophene ring were synthesized under microwave irradiation. Their pharmacological activity toward bacteria and fungi inhibition was screened and compared to the references Chloramphenicol and Trimethoprim/sulphamethoxazole. The antimicrobial results of the investigated compounds revealed prom...