must necessarily be out of date before it is completed. The same remark applies, with perhaps less force, to a book on modern drugs; this "however is a short book and the authoress has managed to keep pretty well up to date with her subject. An exception is the omission of any details regarding sulphathiazole, a drug that has now been in use, in America at any rate, for some time, and is provin...

Huanglongbing (HLB) is a serious citrus disease that threatens the citrus industry. In previous studies, sulfonamide antibiotics and heat treatment suppressed 'Candidatus Liberibacter asiaticus' (Las), but did not completely eliminate the Las. Furthermore, there are few reports studying the bacterial microbiome of HLB-affected citrus treated by heat and sulfonamide antibiotics. In this study, c...

,YIn a previous study (Sevag and Gots, 1948) on the effects of various drugs on the pneumococcal dehydrogenase systems it was found that, whereas acriflavine, atabrine, propamidine, and optochin could inhibit these systems, high concentrations of sulfonamides had no effect. Other investigators (Mellon aind Bambas, 1937; Brazda and Rice, 1942; Fox, 1942; Clifton and Loewinger, 1943) have reporte...

High resolution X-ray diffraction data on forms I-IV of sulfathiazole and neutron diffraction data on forms II-IV have been collected at 100 K and analyzed using the Atoms in Molecules topological approach. The molecular thermal motion as judged by the anisotropic displacement parameters (adp's) is very similar in all four forms. The adp of the thiazole sulfur atom had the greatest amplitude pe...

By E. KODICEK, M.D., Ph.D., AND K. J. CARPENTER, MA., Ph.D. I N OUR previous paper’ we described the development of a macrocytic normochromic anemia in rats fed on synthetic diets containing i per cent sulfasuxidine, and maintained in a state of chronic pteroylglutamic acid (PGA) deficiency. The blood picture of these rats was similar to the nutritional anemias of other species, caused by a PGA...

A liquid chromatographic (LC) method for determining 14 sulfonamide (SA) (sulfanilamide, sulfadiazine (SDZ), sulfathiazole, sulfapyridine, sulfamerazine (SMR), sulfamethazine (SMZ), sulfamethizole, sulfamethoxypyridazine, sulfachloropyridazine (SCP), sulfamonomethoxine, sulfadoxine, sulfamethoxazole, sulfadimethoxine (SDM), and sulfaquinoxaline (SQX)) residues in edible catfish, shrimp and salm...

more and better penicillin we should come to the stage of attacking it successfully. Bigger's (1946) researches showed that penicillin and sulphathiazole when used together exert a synergic action on Bad. typhosum. In consequence of this research McSweeney (1946) treated six cases of typhoid fever in adults with full doses of sulphathiazole and large doses of penicillin with apparently remarkab...