SUPERFICIAL ocular infections, for example blepharitis, are better treated by local applications than by systemic therapy. Local applications of antibiotic and chemotherapeutic agents are also of value in reducing the incidence of infection after corneal injury. Sulphacetamide is most commonly used but, although its value in the prevention of corneal infection is well established (Cameron, 1949...

conclusions this method can be appropriate to estimate sensitive issues; however, lack of understanding the method or doubting the confidentiality of the responses can lead to bias in the results. that is to say, if the instructions are introduced better, the level of trusting the method will increase and accordingly more reliable responses can be obtained. more studies under controlled conditi...

the narcotic drugs business find its abusement, nowadays, have been one of the most basic political, economic, health, cultural anti-family disorders in almost all over the world. despite all technologic anti cultural developments, it seems that the tendency and interest of producers, distributors and users of these drugs in all different age levels are growing up increasingly. unfortunately, t...

background microencapsulation is a useful method to prolong a drug release from dosage forms and to reduce its adverse effect (1) among various available methods. the microencapsulation of hydrophilic active ingredients requires the use of a polar dispersing phase such as a mineral oil. acetone/paraffin systems are conventionally used. objectives the current study aimed to investigate two diffe...

Abstract In this study, magnetic-dispersive solid-phase extraction coupled with ion pair-dispersive liquid–liquid micro-extraction (MSPE-i-DLLME) was used to the pre-concentration and of five sulfonamides residues (sulfadiazine, sulfathiazole, sulfacetamide, sulfamethazine sulfamethoxazole) in animal foodstuffs. The are extracted using magnetic carbon nanocomposite then eluted acetonitrile. DLL...

results there was significant reduction in anger symptoms of drug-dependent individuals after gross model based emotion regulation training (ert) (p < 0.001). moreover, the effectiveness of the training on anger was persistent in the follow-up period. conclusions symptoms of anger in drug-dependent individuals of this study were reduced by gross model-based emotion regulation strategies trainin...

non-medical use of prescription drugs (also known as medication diversion) is a common problem in middle and low income countries where monitoring capacities and law enforcement mechanisms are not efficiently developed (1-3). prescribed central nervous system (cns) stimulants, sedative hypnotics and long-lasting opioids are the most important drugs diverted throughout the world (1-4). non-medic...

A number of genetic systems are described which involve the use of the yeast Saccharomyces cerevisiae. The systems may be used to detect the production of aneuploid cells produced during both mitotic and meiotic cell division in the presence of genetically active chemicals. During mitotic cell division, monosomic colonies (2n - 1) may be detected by plating upon selective medium. Increases in s...

The present investigation was undertaken to evaluate the possible ocular phototoxicity of drugs used in ophthalmic formulations. Sulphacetamide, ketoconazole, voriconazole, diclofenac, and ketorolac were assessed in the concentrations available in the market for their ocular use. The suitable models viz Hen's Egg Test Chorioallantoic Membrane (HET-CAM) test, Isolated Chicken Eye (ICE) test, and...

personalized medicine aims is to supply the proper drug to the proper patient within the right dose. pharmacogenomics (pgx) is to recognize genetic variants that may influence drug efficacy and toxicity. all things considered, the fields cover a wide area, including basic drug discovery researches, the genetic origin of pharmacokinetics and pharmacodynamics, novel drug improvement, patient gene...