Cellulase production study was performed in shake flask and bioreactor system using Cellulomonas cellulans NRRL B 4567 for initial substrate concentration from S0 = 2 to 12 g L . The growth, substrate uptake profile and enzyme activity at different initial substrate concentrations were measured. The results inferred the presence of substrate inhibition kinetics. Various substrate inhibition mod...

Among one dimensional nanomaterials, TiO2 nanorods have found important applications in various industries due to optical, photocatalyst and self-cleaning properties. In this research, at first TiO2 nanorods were synthesized on a glass substrate by hydrothermal method. Then a thin film of TiO2 particles was dip coated (as seed layer) on the substrate. After that, hydrothermal synthesis of TiO2 ...

In vertebrates there are two cholinesterases, with differences in catalytic behaviour with respect to substrate concentration: butyrylcholinesterase displays an increased activity at low substrate concentrations, whereas acetylcholinesterase displays inhibition by excess substrate. In two invertebrates, Drosophila melanogaster and Caenorhabditis elegans, we found cholinesterases that showed bot...

A positive correlation between blood pressure and renin substrate concentration is found in a wide variety of conditions in human beings and in animal experiments. The evidence concerning this relationship is reviewed and the exceptions are discussed. The frequent positive correlation between renin substrate and elevated blood pressure suggests that increased renin substrate concentration may b...

The response of an amperometric biosensor at mixed enzyme kinetics and diffusion limitations was modelled digitally in the case of substrate inhibition. Digital simulations were carried out using a finite difference technique. Calculations showed complex kinetics of biosensor response. At low enzyme activity and substrate concentration (S0), the response of the sensor looks like it is limited b...

The specific consumption rate of substrate, as well as the associated specific growth rate, is an essential parameter in the mathematical description of substrate-limited microbial growth. In this paper we develop a completely new kinetic model of substrate transport, based on recent knowledge on the structural biology of transport proteins, which correctly describes very accurate experimental ...

The individual and interactive effects of initial pH, temperature and initial substrate concentration on the growth of Clostridium pasteurianum was investigated in this study. Statistics based experimental designs are applied to optimize the process parameters for biomass concentration. The biomass concentration (g/l) was evaluated at various levels of initial substrate concentration, temperatu...