نتایج جستجو برای: substitution lines

تعداد نتایج: 272050  

2012
Mine Yarim Meric Koksal Irem Durmaz Rengul Atalay

A series of novel 1-(4-substitutedbenzoyl)-4-(4-chlorobenzhydryl)piperazine derivatives 5a-g was designed by a nucleophilic substitution reaction of 1-(4-chlorobenzhydryl)piperazine with various benzoyl chlorides and characterized by elemental analyses, IR and (1)H nuclear magnetic resonance spectra. Cytotoxicity of the compounds was demonstrated on cancer cell lines from liver (HUH7, FOCUS, MA...

Journal: :international journal of molecular and cellular medicine 0
paulrasu kodisundaram department of chemistry, annamalai university, annamalai nagar-608002, tamilnadu, india. arul duraikannu department of clinical neurosciences, university of calgary, calgary, alberta t2n 4n1, canada. thirunavukkarasu balasankar chemistry section, feat, annamalai university, annamalai nagar-608002, tamilnadu, india. pravin sundarao ambure drug theoretics and cheminformatics laboratory, department of pharmaceutical technology, jadavpur university, jadavpur, kolkata, 700032, india. kunal roy manchester institute of biotechnology, university of manchester, manchester m1 7dn, great britain.

the current study highlights the in vitro antioxidant and antitumor activity of the previously-synthesized hydrazone derivatives against various free radicals and human cancer cell lines, respectively. the anticancer efficacies of the compound were tested by measuring cytotoxicity in cancer cell lines hela, a549, and non-cancerous nl20 cells. compounds possessing electron-donor methoxy and meth...

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