subcutaneous metastatic nodules are an uncommon first sign of underlying cancer. cutaneous metastasis occurs in 0.8% to 4% of all cancer patients and less than 5% in those with lung cancer. these metastases are usually single or multiple painless nodules that may be mobile or fixed. cutaneous metastases from the lung are not very common and indicate a worse prognosis. the limited literature on ...

beta2-Microglobulin accumulation with resultant tumor formation is a known albeit rare complication of long-term hemodialysis. Although these tumors may occur in various locations, subcutaneous shoulder nodules are very infrequent. We report a patient with end-stage kidney failure who had been on hemodialysis for 16 years and noted left shoulder nodules after initiation of hemodialysis; these n...

tuberculos gumma is one of the various clinical manifestations of cutaneous tb that is characterized by non tender, undolent subcutaneous nodules which progressively involve the skin and take the appearance of an ulcer. in this article, we present two young patients, affected with tuberculos gumma. one of them, presented with multiple abcesses on the face and extremities, associated with pulmon...

Background & Objective: Abdominal cutaneous and subcutaneous nodules are uncommon lesions which may be benign or malignant. Majority of the malignant nodules are metastatic in origin and may be the initial presentation of primary malignancy, hence an early diagnosis is important. Our aim was to find out the spectrum of lesions (both non-neoplastic and neoplastic) that present as cutaneous and s...

Weber and Freudenthal (1936-7), Weber (1943, 1944, 1947, 1948), and Fletcher (1946, 1947) have noted the rare occurrence of subcutaneous nodules in rheumatoid arthritis which consisted almost entirely of lipoid, and have designated such cases by various names to differentiate them from the " common " type of rheumatoid arthritis subcutaneous nodule. During the clinical examination of seventy ca...

A 47-year-old Japanese housewife was referred to our hospital with asymptomatic subcutaneous nodules on her forearms. She first noticed the subcutaneous nodules 10 years previously, and they had gradually increased in both size and number. They were not associated with any pain or tenderness. Her family history and past clinical history were unremarkable. Physical examination revealed multiple,...

OBJECTIVES To determine whether the Epstein-Barr virus is present in synovial membranes and subcutaneous nodules of patients with rheumatoid arthritis. METHODS A sensitive in situ hybridisation technique was applied to tissue sections of 11 synovial membranes and five rheumatoid nodules. RESULTS Cells carrying the Epstein-Barr virus were not detected using EBER and BHLF1 oligonucleotides in...

Persistent subcutaneous nodules may arise after vaccination or allergen desensitization. The swelling might appear as a result of a specific histiocytic reaction to aluminum, which is used in many preparations to hasten immune response. A wide range of such vaccines are used in national childhood vaccination programs. Such nodules are frequently itchy or painful with local skin alterations. The...