BACKGROUND Folic acid supplementation is effective in reducing the risk of neural tube defects (NTDs). However, the use of folic acid is low among rural women in China. Nutrition education can provide information about folic acid and encourage its use. The primary objective of this study was to test the effectiveness of a village-based nutrition intervention on folic acid use among rural women....

BACKGROUND Taking folic acid supplements before pregnancy to reduce the risk of a neural tube defect (NTD) is especially important in countries without universal folic acid fortification. The extent of folic acid supplementation among women who had antenatal screening for Down's syndrome and NTDs at the Wolfson Institute of Preventive Medicine, London between 1999 and 2012 was assessed. METHO...

Food fortifi cation with synthetic folic acid (pteroyl monoglutamic acid) remains a source of debate in terms of benefi t versus issues of safety and consumer choice. Several countries have adopted mandatory folic acid fortifi cation. A decision to proceed in Australasia was made in June, 2007. We report the case of a woman who had three episodes of type I hypersensitivity, including ana phylax...

the cause of neural tube defects (ntds) is multifactorial and in this case folic acid has an important role. since the neural tube is closed during 21-28 days of pregnancy, most of women are not informed about their pregnancy at this time, and as a result the golden time of folic acid consumption is missed. the aim of this study was evaluating the performance of pregnant women attending to tehr...

background: gastric cancer is the fourth common malignancy and the second prevalent cause of cancer death in the world. genetic and environmental factors play an important role in the development of this cancer. nutritional and epidemiological studies have indicated that folate status modulates the risk of developing cancer and apoptosis has been reported to play a decisive role in precancerous...

Enzyme induction in Escherichia coli is stimulated by certain 5-amino-2,4-bis(substitutedamino)pyrimidines (Kunkee, 1960a). Other 2,4diaminopyrimidines have been reported to be antagonists of folic acid (Hitchings et al., 1952; Doctor, 1956). Since there are indications that the stimulation of enzyme induction involves nucleic acid metabolism (Kunkee, 1960b) and since folic acid is involved in ...

OBJECTIVE Folic acid food fortification has successfully reduced neural tube defect-affected pregnancies across Canada. The effect of this uncontrolled public health intervention on folate intake among Canadian children is, however, unknown. Our objectives were to determine folic acid intake from food fortification and whether fortification promoted adequate folate intakes, and to describe foli...

Periconceptional use of folic acid alone or in multivitamin supplements is effective for the primary prevention of neural-tube defects. The Hungarian randomized and two-cohort controlled trials showed that periconceptional multivitamin supplementation can reduce the occurrence of some other structural birth defects, i.e. congenital abnormalities. These findings were supported by many, but not a...

Folic acid plays an important role in the prevention of neural tube defects (e.g., spina bifida and anencephaly), heart defects, facial clefts, urinary abnormalities, and limb deficiencies. Milk and milk products serve as a potential source for folic acid fortification because of the presence of folate-binding proteins that seem to be involved in folate bioavailability. Although milk is not a g...