Acacia nilotica is a widely used plant in traditional medical practice in Northern Nigeria and many African countries. The aim of this study was to determine the toxicological effects of a single dose (acute) and of repeated doses (sub-acute) administration of aqueous extract of A. nilotica root in rodents, following our earlier study on antiplasmodial activity. In the acute toxicity test, thre...

Uvaria chamae is used in the treatment of sickle cell crisis Benin. The aim this work to determine safety roots aqueous extract wistar rats. was obtained by maceration. tests for Acute Oral Toxicity (AOT) and Sub-Chronic (SCT) respectively forced gavage a single dose 2000 mg / Kg 200 body weight 28 days were performed on female Wistar animals, serum creatinine, transaminases number white blood ...

the acute toxicity of a malaysian crude oil to red snapper, lutjanus argentimaculatus, blacktiger shrimp and penaeus monodon were investigated. the animals were exposed to water solublefractions (wsf) of crude oil in a flow-through bioassay system and the toxicants were analyzed by gaschromatography (gc) and gas chromatography and mass spectrometer (gc-ms). the 96 h lc50 valuesof the wsf of cru...

malathion is one of the most commonly used pesticides in agriculture. this study was aimed to investigate the acute toxicity of malathion as an aquatic pollutant on the behavior and hematological indices in indian carp ( cirrhinus mrigala ). a static experiment was conducted and 1, 24, 48, 72 and 96 hrs lc 50 values of malathion for the test fish were estimated as 14.55 mg/l, 12.48 mg/l, 11.56 ...

Starch hyaluronate is used as a new superdisintegrating agent in the development of fastdissolving tablets poorly soluble drugs because its improved biocompatibility, and hydrophilicity. The purpose this study to assess acute subacute toxicity profiles starch Wistar rats. was administered rats single-dose monitored for seven days. male female were 28-day sub-acute that examined effects oral dos...