Large concentrations of the beta-amino acid, taurine, can be found in many forebrain areas such as the basolateral amygdala, a portion of the limbic forebrain intimately associated with the regulation of fear/anxiety-like behaviors. In addition to its cytoprotective and osmoregulatory roles, taurine may also serve as an agonist at GABA(A)- and strychnine-sensitive glycine receptors. In this lat...

The effect of intravenous strychnine and the GABA antagonists picrotoxin and bicuculline upon the discharge pattern of center-surround-organized cat retinal ganglion cells of X and Y type were studied. Stimuli (mostly scotopic, and some photopic) were selected such that responses from both on and off-center cells were either due to the center, due to the surround, or clearly mixed. Pre-drug con...

Elucidating the structure of complex molecules is difficult at low magnetic fields due to the overlap of different peak multiplets and second-order coupling effects. This is even more challenging for rigid molecules with small chemical shift differences and with prochiral centers. Since low-field NMR spectroscopy is sometimes presumed as restricted to the analysis of only small and simple molec...

introduction: due to dissimilarities in the availability of poisons in different areas and lack of enough control over the purchase and sale of some dangerous rodenticides, it is prudent to establish the distribution of rodenticide poisoning in each region. therefore, this study was performed to evaluate the demographic factors, types of poisons, duration of hospitalization and mortality of pat...

Objective Royal jelly is a honey bee secretion with beneficial effects on the nervous system. The present study aims to investigate of royal in reducing seizure and anxiety-like behaviors Syrian rats. Methods This an experimental study. In model, 25 male white rats were randomly divided into five groups: Control, 100 mg/kg, 200 400 phenobarbital. After 30 minutes, strychnine was injected induce...