The betaine transporter (BGT1) protects cells in the hypertonic renal inner medulla by mediating uptake and accumulation of the osmolyte betaine. Transcriptional regulation plays an essential role in upregulation of BGT1 transport when renal cells are exposed to hypertonic medium for 24 h. Posttranscriptional regulation of the BGT1 protein is largely unexplored. We have investigated the distrib...

The mechanism by which cells increase their rate of glucose uptake in response to stress is unclear. Using an immunofluorescence technique to localize the glucose transporter protein in BHK cells, we found that hyperthermia, treatment with arsenite, infection with vesicular stomatitis virus or Semliki Forest virus, and treatment with insulin cause the transporter to move from an intracellular s...

We used a finite element model to interpret anti-correlated pressure variations at the base of a glacier to demonstrate the importance of stress redistribution in the basal ice. We first investigated two pairs of load cells installed 20 m apart at the base of the 210 m thick Engabreen glacier in Northern Norway. The load cell data for July 2003 showed that pressurisation of a subglacial channel...

The focus of this research is the stress laminated timber cellular deck. The testing program has involved application of loads that modelled both the design serviceability and design ultimate conditions, and identified slip and load redistribution mechanisms, which occur at the limit state of linear composite behaviour. This paper presents a summary of the results of this testing and discusses ...

A temperature and rate-dependent crystal plasticity framework has been used to examine the temperature sensitivity of stress relaxation, creep and load shedding in model Ti-6Al polycrystal behaviour under dwell fatigue conditions. A temperature close to 120°C is found to lead to the strongest stress redistribution and load shedding, resulting from the coupling between crystallographic slip rate...

Background. Thallium reinjection immediately after stress-redistribution imaging identifies ischemic but viable myocardium in as many as 50%o of the regions characterized by conventional redistribution imaging as irreversibly injured. However, we have previously shown that some regions in which irreversible defects persist despite reinjection are metabolically active, and hence viable, by posit...

Background. Thallium reinjection immediately after stress-redistribution imaging identifies ischemic but viable myocardium in as many as 50%o of the regions characterized by conventional redistribution imaging as irreversibly injured. However, we have previously shown that some regions in which irreversible defects persist despite reinjection are metabolically active, and hence viable, by posit...

In this article, the time-dependent stress redistribution analysis of magneto-electro-elastic (MEE) thick-walled sphere subjected to mechanical, electrical, magnetic and uniform temperature gradient as well as moisture concentration gradient is presented. Combining constitutive equations of MEE with stress-strain relations as well as strain-displacement relations results in obtaining a differen...

Among the adaptive-grid methods, redistribution and embedding techniques have been the focus of more attention by researchers. Simultaneous or combined adaptive techniques have also been used. This paper describes a combination of adaptive-grid embedding and redistribution methods on semi-structured grids for two-dimensional invisid flows. Since the grid is semi-structured, it is possible to us...