This laboratory first became interested in hydroxyguanidine as a result of our studies on the mechanism of action of transamidination enzymes. We have found that transamidinases from Streptomyces griseus (2), mammalian pancreas (3) and kidney (4), and chicken and frog liver (5) can catalyze a transfer of the terminal formamidine group of arginine to hydroxylamine, with the formation of hydroxyg...

Streptomyces griseus showed three different modes of changing fatty acids in response to temperature change. In Brevibacterium fermentans, two such responses were found. The responses involved changes in fatty acid branching, unsaturation, or chain length, depending on growth temperature range. Changes in unsaturation of branched-chain acids were characteristic at low growth temperatures.

during 2 years, from march 1987 to april 1989, 600 samples of soil and plant were collected from different cities of northern provinces of iran. out of the six hundred samples 58 actinomycetes, 9 pseudallescheria boydii, 10 sporothrix schenckii, and 4 sporothrix schenckii-like fungi were isolated as the following: streptomyces griseus from 31 samples (38.27%), nocardia asteroides from 8 samples...

Mithramycin and chromomycin A(3) are two structurally related antitumour compounds, which differ in the glycosylation profiles and functional group substitutions of the sugars. Chromomycin contains two acetyl groups, which are incorporated during the biosynthesis by the acetyltransferase CmmA in Streptomyces griseus ssp. griseus. A bioconversion strategy using an engineered S. griseus strain ge...

A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) acts as a microbial hormone that induces morphological development and secondary metabolism in Streptomyces griseus. A diffusible yellow pigment is produced by S. griseus in an A-factor-dependent manner under phosphate depletion. Detailed analysis of the pigment production by S. griseus cultivated in minimal liquid medium containing...