نتایج جستجو برای: stochastic vrp

تعداد نتایج: 126463  

2012
Majid Yousefikhoshbakht Esmaile Khorram

The vehicle routing problem (VRP) is one of the most important combinational optimization problems that has nowadays received much attention because of its real application in industrial and service problems. The VRP involves routing a fleet of vehicles, each of them visiting a set of nodes such that every node is visited by exactly one vehicle only once. So, the objective is to minimize the to...

Journal: :Logopedics, phoniatrics, vocology 2012
Anna Eva Hallin Karin Fröst Eva B Holmberg Maria Södersten

Reference data for speech range profiles (SRP), voice range profiles (VRP), and Voice Handicap Index (VHI) are presented for Swedish males (n = 30). For comparisons, individual data for four male contact granuloma patients are also reported. For the vocally healthy group mean values were: speaking fundamental frequency 123 Hz (SD 12.1), speaking equivalent level, Leq, 72.2 dB (SD 2.1), SRP area...

2014
JOSE CACERES-CRUZ DANIEL GUIMARANS

The Vehicle Routing Problem (VRP) is a well known research line in the optimisation research community. Its different basic variants have been widely explored in the literature. Even though it has been studied for years, the research around it is still very active. The new tendency is mainly focused on applying this study cases to real life problems. Due to this trend, the Rich VRP arises; comb...

2010
Yang Honglin Yuan Jijun

The vehicle routing problem (VRP) is one of the most challenging problems in the optimization of distribution networks. A distribution model, based on analysis of most published literatures, relevant to route arrangement was established for VRP. Meantime, an improved genetic algorithm (IGA) was proposed to overcome both the shortcomings of premature convergence of GA and local search. Inversion...

Journal: :Journal of virology 2013
Andrew S Herbert Ana I Kuehne James F Barth Ramon A Ortiz Donald K Nichols Samantha E Zak Spencer W Stonier Majidat A Muhammad Russell R Bakken Laura I Prugar Gene G Olinger Jennifer L Groebner John S Lee William D Pratt Max Custer Kurt I Kamrud Jonathan F Smith Mary Kate Hart John M Dye

There are no vaccines or therapeutics currently approved for the prevention or treatment of ebolavirus infection. Previously, a replicon vaccine based on Venezuelan equine encephalitis virus (VEEV) demonstrated protective efficacy against Marburg virus in nonhuman primates. Here, we report the protective efficacy of Sudan virus (SUDV)- and Ebola virus (EBOV)-specific VEEV replicon particle (VRP...

Journal: :PLoS ONE 2008
Kurt I. Kamrud Kim D. Alterson Chasity Andrews Laura O. Copp Whitney C. Lewis Bolyn Hubby Deepa Patel Jonathan O. Rayner Todd Talarico Jonathan F. Smith

BACKGROUND The Venezuelan equine encephalitis (VEE) virus replicon system was used to produce virus-like replicon particles (VRP) packaged with a number of different VEE-derived glycoprotein (GP) coats. The GP coat is believed to be responsible for the cellular tropism noted for VRP and it is possible that different VEE GP coats may have different affinities for cells. We examined VRP packaged ...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2005
Stacie M Goldberg Shirley M Bartido Jason P Gardner José A Guevara-Patiño Stephanie C Montgomery Miguel-Angel Perales Maureen F Maughan JoAnn Dempsey Gerald P Donovan William C Olson Alan N Houghton Jedd D Wolchok

PURPOSE Immunization of mice with xenogeneic DNA encoding human tyrosinase-related proteins 1 and 2 breaks tolerance to these self-antigens and leads to tumor rejection. Viral vectors used alone or in heterologous DNA prime/viral boost combinations have shown improved responses to certain infectious diseases. The purpose of this study was to compare viral and plasmid DNA in combination vaccinat...

2016
Eirini Konstantinidi George Skiadopoulos Michael Halling Nikunj Kapadia Alexandros Kostakis Philippe Mueller Michael Neumann Ilias Tsiakas Andrea Vedolin

We explore whether the market variance risk premium (VRP) can be predicted. We measure VRP by distinguishing the investment horizon from the variance swap’s maturity. We extract VRP from actual S&P 500 variance swap quotes and we test four classes of predictive models. We find that the best performing model is the one that conditions on trading activity. This relation is also economically signi...

2012
Matija Gulic

With significant advances in computing power during recent years, increasingly complex variants of the vehicle routing problem (VRP) with added constraints are coming into focus. VRP is a combination of the classical traveling salesman and bin packing problems, with many real world applications in various fields – from physical resource manipulation planning to virtual resource management in th...

Journal: :Inf. Process. Lett. 2006
Enrique Alba Bernabé Dorronsoro

The Vehicle Routing Problem (VRP) is a hard combinatorial problem with numerous industrial applications. Among the large number of extensions to the canonical VRP, we study the Capacitated VRP (CVRP), which is mainly characterized by using vehicles of the same capacity. A cellular Genetic Algorithm (cGA)—a kind of decentralized population based heuristic—is used for solving CVRP, improving seve...

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