background: traditional medicines with anti-diabetic effects are considered suitable supplements to treat diabetes. among medicinal herbs, stevia rebaudiana bertoni is famous for its sweet taste and beneficial effect in regulation of glucose. however, little is known about the exact mechanism of stevia in pancreatic tissue. therefore, this study investigated the possible effects of stevia on pa...

Stevioside is natural non-caloric sweetner isolated from Stevia rebaudiana BERTONI, which has been used as a non-caloric sugar substitute in Japan. Pezzuto et al. demonstrated that steviol shows a dose-dependent positive response in forward mutation assay using Salmonella typhimurium TM677 in the presence of metabolic activation system (Aroclor induced rat liver S9 fraction). Our studies were c...

Following our interest in new diterpene glycosides with better taste profiles than that of Rebaudioside M, we have recently isolated and characterized Rebaudioside IX-a novel steviol glycoside-from a commercially-supplied extract of Stevia rebaudiana Bertoni. This molecule contains a hexasaccharide group attached at C-13 of the central diterpene core, and contains three additional glucose units...

Leaves of Stevia rebaudiana Bertoni have been popularly used as a sweetener in foods and beverages for diabetics and obese people due to their potent sweetener stevioside. In this report, stevioside and steviol were tested for mutagenicity in Salmonella typhimurium strains TA98 and TA100 and for chromosomal effects on cultured human lymphocytes. Stevioside was not mutagenic at concentrations up...

background: stevia rebaudiana bertoni, an important anti-diabetic medicinal plant, becomes an inevitable alternative to sugar. due to the propagation difficulties, tissue culture is the best alternative for rapid mass propagation of stevia plants. objective: the present study was conducted to optimize a protocol for rapid micropropagation of stevia rebaudiana by shoot tip explants and to invest...

We investigated the influence of different conditions (light composition and plant growth regulators (PGRs) in culture media) on morphophysiological parameters Stevia rebaudiana Bertoni vitro vivo. Both PGRs light spectra applied were found to significantly affect morphogenesis. During micropropagation stage S. rebaudiana, optimal growth, with a multiplication coefficient 15, was obtained an MS...

In recent years there has been increasing demand for natural non-nutritive high intensity sweeteners with low-calorie value as an alternative to sucrose. Extracts of the leaves of Stevia rebaudiana (Bertoni), have been known for their sweet taste. Steviosides and rebaudioside-A are the two major diterpenoid glucosides components present in the leaf extracts of the stevia, these glycosides are 3...

Aim: To assess the anticariogenicity of microwave-assisted 0.5% extract of Stevia rebaudiana leaves in high caries risk patients. Materials and methods: Forty-six patients with high risk for caries were selected. They were randomly assigned to two groups; group I was allocated for chlorhexidine (CHX) mouthwash (0.12% Perio-Aid) and group II for S. rebaudiana (0.5% extract of Stevia bio) mouthwa...