As recently reported, there is increasing association between the opportunistic pathogen Stenotrophomonas maltophilia and pulmonary exacerbations in cystic fibrosis (CF) . There has been further literature regarding approaches for surveillance of S. maltophilia in this patient population, potential prediction of clinical outcomes based on such monitoring and, in light of escalating incidence of...

INTRODUCTION Stenotrophomonas maltophilia is an important cause of hospital acquired infection particularly among severely debilitated and immunosuppressed patients. CASE PRESENTATION We report a case of S. maltophilia meningitis in a preterm baby boy after a neurosurgical procedure, successfully treated with trimethoprim-sulfamethoxazole and ciprofloxacin. CONCLUSION This organism should b...

To the Editor: Stenotrophomonas maltophilia has emerged as an important nosocomial pathogen, especially in debilitated and immunocompro-mised persons (1). However, comparatively little is known of the epidemiology of this bacterium, and sources and routes of transmission of S. mal-tophilia are not well understood. The bacterium is widely distributed in the environment, including in plant rhi-zo...

Patients with nosocomial pneumonia caused by Stenotrophomonas maltophilia often receive inadequate empiric antibiotic therapy, potentially increasing mortality. Knowledge of the risk factors associated with S. maltophilia pneumonia may better guide the selection of empiric antibiotic therapy. Potential risk factors for S. maltophilia pneumonia were retrospectively analyzed for critically ill tr...

Stenotrophomonas maltophilia is increasingly identified as an opportunistic pathogen in immunocompromised, cancer and cystic fibrosis (CF) patients. Knowledge on innate immune responses to S. maltophilia and its potential modulation is poor. The present work investigated the ability of 12 clinical S. maltophilia strains (five from CF patients, seven from non-CF patients) and one environmental s...

A total of 18,386 organisms, including 13,224 Enterobacteriaceae, 3536 Pseudomonas aeruginosa, 1254 Acinetobacter spp., and 372Stenotrophomonas maltophilia were collected from Western Europe (WEU; n=10,021), Eastern Europe (EEU; n=4957), and the Asia-Pacific region (APAC; n=3408 [1052 from China]) in 2013-2014 as part of the SENTRY Antimicrobial Surveillance Program and tested by a reference br...

Stenotrophomonas maltophilia CBF10-1 was isolated from a ranch in Fairchilds, Texas, USA. Its genome reveals a highly adaptable microorganism with a large complement of antibiotic and heavy metal resistance genes, efflux pumps, multidrug transporters, and xenobiotic degradation pathways.

Stenotrophomonas maltophilia isolates have been recovered from various clinical samples, including the respiratory tract of cystic fibrosis (CF) patients, but this organism is also widespread in nature. Previously it has been shown that there is a considerable genomic diversity within S. maltophilia. The aims of our study were to determine the taxonomic resolution of restriction fragment length...

25 Stenotrophomonas maltophilia is a multi-drug resistant organism increasingly isolated from the 26 lungs of cystic fibrosis (CF) patients. One hundred twenty-five S. maltophilia isolates from 85 27 CF patients underwent planktonic and biofilm susceptibility testing against 9 different 28 antibiotics, alone and in double antibiotics combinations. When S. maltophilia were grown as a 29 biofilm,...