background and aim: squamous cell carcinoma is the eighth common cancer and forms 94% of oral malignancies. nowadays, many molecular and genetic changes have been known to affect tumoral behavior which might be good for drug production and gene therapy. it has been known that mutated p53, overexpression of p63 as an oncogene and hpv infection are correlated with clinicopathological behavior of ...

telomerase activation is one of the main pathways to immortalize cancer cells. in many kinds of cancer cells, this special reverse transcriptase stabilizes and elongates telomeres and prevents telomere erosion that naturally occurs in every cell division. esophageal cancer is the fifth most frequent cause of cancer death worldwide, and is highly associated with alcohol, smoking, cultural habits...

background: although color doppler ultrasonography (cdus) is useful in the diagnosis of various diseases of the head and neck, flow signals in oral malignant masses are less studied; hence the present study assesses the usefulness of color doppler ultrasonography in quantifying oral squamous cell carcinoma (oscc) vascularization. in addition, we determine the hemodynamic parameters by spectral ...

human papillomavirus (hpv) dna has been identified in esophageal carcinomas. however, the incidence of hpv varies significantly in different geographical locations. in this study, neoplasms from turkmen sahra, a region in golestan province in northeast part of iran, with a high incidence of squamous cell carcinoma were analyzed for the presence of hpv dna. turkmen sahra is located in the cancer...

the previous studies reported some information about prevalence release of high-risk hpv types in hsil or cervical cancer globally and in iran, however, this information is not enough for final judgment about vaccination against hpv or any screening program. the aim of the present study was to assess the hpv type distribution in hsil and icc specimens of women attending shahid beheshti universi...

background: the aim of this study was to present epidemiological aspects of malignant tumor of head and neck in southeast of iran, with a view toward analyzing the age, gender, site distribution and histological types.  methods: all cases with malignant tumor of the head and neck region from 1999 to 2009 were retrieved from the records of cancer registry center of kerman university of medical s...

abstract carcinoma of the vulva has commonly been recognized as a disease of postmenopausal women, but some cases have been reported in young women during pregnancy. medical records were reviewed for a patient with vulvar carcinoma diagnosed in pregnancy. using medline and cross references, pertinent articles were sought and reviewed. a 28-year-old afghan woman in her sixth pregnancy presented ...

introduction: sentinel node mapping has been used for laryngeal carcinoma in several studies, with excellent results thus far.in the current study, we report our preliminary results on sentinel node mapping in laryngeal carcinoma using intra-operative peri-tumoral injection of a radiotracer.   materials and methods: patients with biopsy-proven squamous cell carcinoma of the larynx were included...

this is a case report concerning a 60 years old man who lived for a short period in an endemic area of khuzestan province (neighboring province of persian gulf in iran) for approximately 20 years ago. recently he referred to the urology department of kerman university of medical sciences with hematuria and dysuria. in the sonography a polypoid mass on the bladder floor was observed. in the cyst...

background: abnormal pap smear consists of premalignant or malignant cervical lesions. many of premalignant cervical lesions will never progress to invasive malignancy, or even may regress over the time. thus, there is always a risk of overtreatment of patients with an abnormal pap smear. a long-term follow-up of these patients can reveal final events associated with each  subtype of abnormal p...