Lemongrass oil and d-limonene are typical flavor oils used in the food and cosmetic industries. Lemongrass oil displays some therapeutic properties such as analgesic, antimicrobial, fungicidal, deodorant, etc. Citral, the main active component of lemongrass oil, consists of a mixture of two isomeric acyclic monoterpene aldehydes: geranial and neral. Molecular encapsulation of these flavors was ...

We prepared various types of yuja powders from juice, fruit, and seed (to maintain the unique flavor) by using different homogenization drying methods investigated their physicochemical properties. To this end, ultrasonic high-pressure homogenization, were carried out to obtain mixtures. These mixtures subjected via spray-drying, freeze-drying, microwave vacuum-drying spray-dried, freeze-dried,...

The retention of the enzyme activity of alcohol dehydrogenase (ADH) has been studied in various drying processes such as spray drying. The aim of this study is to encapsulate ADH in mannitol, either with or without additive in order to limit the thermal denaturation of the enzyme during the drying process. The retention of ADH activity was investigated at different drying temperatures. When man...

Microencapsulation protects sensitive nutrients, masks flavors, or enhances delivery. Ratios of maltodextrin and γ-cyclodextrin (20:0, 19:1, and 17:3% w/w) were dissolved in water and mixed with pomegranate juice for spray drying with inlet temperatures of 120, 140, and 160°C. The effects on physical properties (water activity, % water content, color, pH, soluble solids (Brix), and methyl cellu...

The objective of the present study was to entrap isoniazid, an Antitubercular drug, in cross linked chitosan matrix and study in vitro lung deposition of powdered chitosan microspheres using Andersen cascade impactor. Ionic cross linker Tripolyphospate was used to make cross linked chitosan microspheres to achieve sustained drug release. Chitosan microspheres were prepared by spray drying metho...

Background: Amikacin as a liposomal solution for nebulization is an antibiotic under study for the treatment of Pseudomonas aeruginosa infections in cystic fibrosis patients. In a previous study, the respirability of amikacin dry powders obtained by spray drying was maximized using a Design of Experiment (DoE) approach. This study intended to explore the most influential process and formulation...

Polyelectrolyte complexes (PECs) are attractive carriers with recognized potential to enhance oral delivery of poorly soluble high-dosed low-molecular-weight drugs. The formulation solid dosage forms requires the drying PECs, which may affect their physicochemical and biopharmaceutical properties. aim this study was investigate effect spraydrying on properties ibuprofen-loaded chitosan/xanthan ...

An ambient method for rapid monitoring and quantitation of drugs of abuse in dried blood spots was developed using paper spray tandem mass spectrometry (PS-MS).

Citation: Haggag YA and Faheem AM (2015) Evaluation of nano spray drying as a method for drying and formulation of therapeutic peptides and proteins. The high sensitivity of peptides and proteins to physicochemical stresses during processing and storage is the major hurdle against its pharmaceutical applications. Peptide-based drug formulations are commonly prepared as solid dosage forms becaus...

Bovine plasma was inoculated with porcine epidemic diarrhea virus (PEDV) at an average final titer of 4.2 log10 TCID50/mL to determine the effect of spray drying on viral inactivation. Using a laboratory scale drier, inoculated plasma was spray dried at 200 °C inlet temperature and either 70 or 80 °C throughout substance. Both liquid and dried samples were subjected to three passages on VERO ce...