The risk of neurological diseases increases with age. In WAG/Rij rat model of absence epilepsy, the incidence of epileptic spike-wave discharges is known to be elevated with age. Considering close relationship between epileptic spike-wave discharges and physiologic sleep spindles, it was assumed that age-dependent increase of epileptic activity may affect time-frequency characteristics of sleep...

In rat models of absence epilepsy, epileptic spike-wave discharges appeared in EEG spontaneously, and the incidence of epileptic activity increases with age. Spike-wave discharges and sleep spindles are known to share common thalamo-cortical mechanism, suggesting that absence seizures might affect some intrinsic properties of sleep spindles. This paper examines time-frequency EEG characteristic...

The fluid–structure interaction (FSI) effect has a significant impact on the static and dynamic performance of aerostatic spindles, which should be fully considered when developing new product. To enhance overall two-round optimization design method for spindles considering FSI is proposed in this article. An spindle optimized to elaborate procedure method. In first-round design, geometrical pa...

The traditional probabilistic-based lifetime evaluation methods for motorized spindles ignore the effects of load dynamic and structural difference. Therefore, we propose a model-based estimation method that combines these to improve results spindles, especially at design stage. Given bearing dramatically influences reliability this paper also designs shaft-bearing-toolholder based on model est...

A-interrupted alpha: the normal waking 10.per-second rhythm dominates the pattern B-Zozu voltage: the alpha rhythm is lost C-spindles: short groups (“spindles”) of 14-per-second waves appear and also random “delta” * waves 0.2 second or more in length D-spindles plus random: both types of wave increase in voltage and the delta waves become longer E-random: the 14.per-second waves become inconsp...

Accuracy in chromosome segregation depends on the assembly of a bipolar spindle. Unlike mitotic spindles, which have roughly equal amounts of kinetochore microtubules (kMTs) and nonkinetochore microtubules (non-kMTs), vertebrate meiotic spindles are predominantly comprised of non-kMTs, a large subset of which forms an antiparallel "barrel" array at the spindle equator. Though kMTs are needed to...

A-interrupted alpha: the normal waking 10.per-second rhythm dominates the pattern B-Zozu voltage: the alpha rhythm is lost C-spindles: short groups (“spindles”) of 14-per-second waves appear and also random “delta” * waves 0.2 second or more in length D-spindles plus random: both types of wave increase in voltage and the delta waves become longer E-random: the 14.per-second waves become inconsp...